Ç̲ÑÒ (Contents)
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Ðåäàêö³éíà ðàäà (Editorial Board) |
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Çì³ñò (Contents) |
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ÎÃËßÄÈ (REVIEWS) |
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| ÊÎÍÖÅÏÖÈß ÁÎÐÜÁÛ Ñ ÈÍÔÅÊÖÈßÌÈ ÍÀ ÑÎÂÐÅÌÅÍÍÎÌ ÝÒÀÏÅ Ôðîëîâ À.Ô. THE CONCEPT OF STRUGGLE AGAINST INFECTION CONTAMINATIONS AT THE PRESENT STAGE Frolov A.F. In article
the review of the literature concerning a modern state of struggle
against contagions in modern condi-tions is presented. It is shown an
essential role of persistent viruses in complication of an epidemic
situation in the world recently. Paths of the further struggle against
epidemies of dangerous infection contaminations are offered. Strat-egy
of behaviour of the state in conditions of threat of modern epidemies
is offered.
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1-5 |
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| ÈÇÌÅÍÅÍÈÅ
ÑÎÑÒÀÂÀ ÏÐÈÑÒÅÍÎ×ÍÎÉ ÌÈÊÐÎÔËÎÐÛ ÊÀÊ ÏÎÊÀÇÀÒÅËÜ ÝÔÔÅÊÒÈÂÍÎÑÒÈ ÏÐÈÌÅÍÅÍÈß
ËÅ×ÅÁÍÛÕ ÏÐÅÏÀÐÀÒΠÏÐÈ ÝÊÑÏÅÐÈÌÅÍÒÀËÜÍÎÌ ÄÈÑÁÈÎÇÅ Ãàòàóëøèí À.Ã., Áëèíêîâà Ë.Ï., Ìèõàéëîâà ÍÀ., Åëêèíà ÑÈ., Ãàéäåðîâ À.À., Êàëèíà Í.Ã., Ãîðîáåö Î.Á. CHANGE OF COMPOSITION OF THE MICROFLORA AS THE EFFICIENCY FACTOR OF APPLICATION OF MEDICAL DRUGS AT EXPERIMENTAL DISBIOSIS Gataulin AG, Blinkova LP, Michaylova NA, Yolkina SI, Gayderov AA, Kalina NG, Gorobetc OB. In article
results of studying of spirulina influence and ciprofloxacin on a
breeding of microorganisms are resulted. It is shown, that spirulina in
quantity of 1 mg has caused an essential quantitative change of
microorganisms. Number lac + and lac-microorganisms has compounded
10:1. However the augmentation of a spirulina dose has sharply reduced
a level 1àñ + enterobacteria (more than in 200 times). Similar
influence of the same doses of a complex of spirulina me-tabolites also
has been taped in vitro concerning E.coli, Shigella, Staphyiococcus,
Streptococcus. For carrying out of correction of a microflora at
disbiosis an intestine it is necessary to consider features of action
of the injected drug not only on a concrete microorganism, but also on
its interrelation with other microflora, including, the same sort.
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6-10 |
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| ÈÑÏÎËÜÇÎÂÀÍÈÅ ÎÒÕÎÄÎÂ ÈÇ ÌÎÐÅÏÐÎÄÓÊÒÎÂ Â ÏÈÒÀÒÅËÜÍÛÕ ÑÐÅÄÀÕ ØìûãàëåâàÒ.Ï.. Áëèíêîâà Ë.Ï., Ãîðîáåö Î.Á., Ìóõèí Â.À., Íîâèêîâ Â.Þ. RECOVERY FROM SEAFOODS IN NUTRIENT MEDIUMS Schmigaleva TP, Blinkova LP., Gorobetc OB, Muhin VA, Novikov V Y. In work
results of studying of processing waste of seafoods as components of
nutrient mediums for cultivation of microorganisms are presented. It is
shown, that use of the hydrolysates tested by us from waste of sea
crafts in structure of nutrient agar of nutrient broth allows to evolve
as the most suitable for the further studying a breakage of the shrimp,
and also waste of the Kamchatka crab and kukumaria.
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11-17 |
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| ÐÎÇÐÎÁÊÀ ÌÅÒÎIJ ÒÐÀÍÑÔÎÐÌÀÖ²¯ ²ÄÕÎIJ ÃÀÌÀÃËÎÁÓ˲ÍÎÂÎÃÎ ÂÈÐÎÁÍÈÖÒÂÀ Ó ÔÎÐÌÓ, ÄÎÑÒÓÏÍÓ ÄËß Ì²ÊÐÎÎÐÃÀͲÇ̲ Îñîëîä÷åíêî Ò.Ï., ͳêîëàºíêî Â.Ì., Áîæêî Ì.Ã. , Ùåò³í³íà Â.Ì.,Øòèêåð Ë.Ã. WORKING OUT METHODS FOR TRANSFORMATION WASTE OF GAMAGLOBULIN MANUFACTURE IN FORM WHICH ACCESSIBLE FOR BACTERIUMS
Osolodchenkov TP, Nikolayenko VM, Bogzko MG, Schetinina VM, Schtiker LG. Receiving regimes of nutrient basis in the way overdoing waste gamaglobuline manufacture of pancreas which let to get nutrient forms for microorganisms was worked out. You can see possibility of their using constructions of nutrient mediums. Key words: nutrient basis, waste of manufacture, construction of mediums, cultivation |
17-21 |
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| ÐÎÇÐÎÁÊÀ ÆÈÂÈËÜÍÎÃÎ ÑÅÐÅÄÎÂÈÙÀ ÄËß ÎÄÅÐÆÀÍÍß Á²ÎÌÀÑÈ STAPHYLOCOCCUS AUREUS Îñîëîä÷åíêî Ò.Ï., Ïàñ³÷íèê Ò.Î., ͳêîëàºíêî Â.Ì., Øòèêåð Ë.Ã., Áàòðàê Î.À. , Çàâàäà Í.Ï. , Ðÿáîâà ².Ñ., Ùåò³í³íà Â.Ì. WORKING OUT NUTRIENT MEDIUM FOR RECEIVING BIOMASS STAPHYLOCOCCUS AUREUS Osolodchenko TP, Pasichnik TO, Nikolayenko VM, Schtiker LG, Batrak OA, Zavada NP, Ryabova IS, Schetinina VM Nutrient
medium was worked out on basis of acid hydrolysate of active silt for
biomass cultivation Staphylococcus aureus. Nutrient medium provide
enough activity increase and have low prime cost in compare with
prototype.
Key words: nutrient basis, construction of mediums, cultivation |
22-25 |
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| ÎÑÎÁËÈÂÎÑÒ² ÄÈÍÀ̲ÊÈ ÇÀÕÂÎÐÞÂÀÍÎÑÒ² ÍÀ ÃÐÈÏ ÒÀ Ãв Ó ÐÎÁ²ÒÍÈʲ ÂÈÐÎÁÍÈÖÒÂÀ ÃÀÇÎÐÎÇÐßÄÍÈÕ ËÀÌÏ Ïëîâåöüêà ².À. FEATURES OF DYNAMICS OF THE INFLUENZA AND ACUTE RESPIRATORY VIRUS INFECTION OF THE GAS-DISCHARGE LAMPS’ PLANT Plovetskaya IA. The
results of own researches are reported. In the Poltava Gas-Discharge
Lamps’ Plant, the legibly expressed seasonal regularity of dynamics of
the influenza + ARVI (acute respiratory virus infection) morbidity with
maxima of quantity and general duration of cases in the second half of
winter and minima in the second half of summer is observed. The
duration of a separate case has three almost identical maxima in
January, May and September. The trends of quantity of cases of
influenza + ARVI diseases and general quantity of days of disease
indicate existence of the legible long-term tendency to ascending of
these parameters. The mean duration of one case practically does not
change. Dynamics of all parameters has an the expressed periodic
component, which requires further research, as well as factors
conditioning it. Similar researches on other plants with some harmful
working conditions are necessary for the elucidation of the role of the
harmfulness of production.
Keywords: production of gas-discharge lamps, influenza and ARVI, morbidity dynamics, trend, periodicity. |
25-29 |
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| HERPES VIRAL INFECTION AND STRUCTURAL CHANGES IN WOMEN'S PLACENTA Torianik I., Panchenko L., Kuchma I., Volyansky A., Volyansky D., Kazmirchuk V., Radchenko E., Popova N., Makarenko V Placental
preparations stained with hematoxylin-eosin and according to Van Hison
were studied by histologi-cal method. Typical destructive vascular
lesions with pronounced disorganization of endothelial wall, signs of
stasis and thrombosis in 8 preparation of placenta were established in
morphological investigations. In placental emulsions with the help of
immunofermental method Herpes simplex virus of the 1-st type was
detected.
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34-37 |
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| ÎÑÎÁÅÍÍÎÑÒÈ ÈÌÌÓÍÈÒÅÒÀ Ó ÄÅÒÅÉ, ÁÎËÜÍÛÕ ÒÓÁÅÐÊÓËÅÇÎÌ È ÖÈÒÎÌÅÃÀËÎÂÈÐÓÑÍÎÉ ÈÍÔÅÊÖÈÅÉ Ñìåëÿíñêàÿ Ì.Â., Âîëÿíñêèé Þ.Ë., Ïåðåìîò Ñ.Ä., Øìàòüêî Ñ.À. FEATURES IMMUNITY AT CHILDREN SICK OF THE TUBERCULOSIS AND CITOMEGALOVIRUS INFECTION At
children sick combination of infections – TBC+CMV-, it is marked
antigen-induced immunosupressis, caused persistentnia CMV, which the
immune inflammation against itself (specific immunosupressis) and
nonspecific against micobacteria tuberculosis (nonspecific
immunosupressis) specifically brakes. It is necessary for taking into
account at carrying out immunorehabilitation of patients with a
tuberculosis.
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38-42 |
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| ÀÍÒÀÃÎͲÑÒÈ×ÍÀ ÀÊÒÈÂͲÑÒÜ ÏÐÎÁ²ÎÒÈÊ²Â Ó Â²ÄÍÎØÅÍͲ ̲ÊÐÎÎÐÃÀͲÇ̲ Ðèæåíêî Ñ.À. ANTAGONISTIC ACTIVITY PROBIOTICS IN RESPECT OF MICROORGANISM Rizenko SA The
results of research of antagonistic action probiotics Colibacterinum,
Bificol, Bifidumbacterinum, Lactobacterinum, Linex, Biosporinum and
A-bacterinum on conditional – pathogenics microorganisms resistance
antibiotics, C.albicans and N.meningitidis are submitted. The various
antagonistic activity probiotics is fixed concerning investigated
microorganisms from absence her up to expressed. The marked
antagonistic action probiotics it needs the further study for
possibility application them in complex therapy of diseases caused
resistance strains of microorganisms, and also for study epidemic
strains as an epidemiological marker.
Key words: Probiotic, antagonistic activity, resistance antibiotics |
43-47 |
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| HELICOBACTER PYLORI-HERPESVIRIDAE ÀÑÑÎÖÈÀÖÈÈ Â ÝÒÈÎÏÀÒÎÃÅÍÅÇÅ ÍÅÎÏËÀÑÒÈ×ÅÑÊÈÕ ÏÎÐÀÆÅÍÈÉ ÆÅËÓÄÊÀ. ÑÎÂÐÅÌÅÍÍÛÅ ÀÑÏÅÊÒÛ ÈÇÓ×ÅÍÈß ×åðíÿâñêèé Â.È., Áèðþêîâà Ñ.Â., Ìàðòûíîâ À.Â., Ñìåëÿíñêàÿ Ì.Â., Áåëÿåâñêàÿ Ñ.Þ., Ïåðåìîò Ñ.Ä., Êðèâîðó÷êî È.À., Ðîìàíîâà Ì.Â. Ðàä÷åíêî À.À., Ñåéäàìåòîâ Ð.Ð. THE ROLE OF HELICOBACTER PYLORI-HERPESVIRIDAE ASSOCIATION IN ETHYOPATHOGENESIS OF NEOPLASTIC INJURIES OF STOMACH. MODERN ASPECTS OF STUDY Chernyavsky VI, Birukova SV, Martynov AV, Smelyanskaya MV, Belyayevskaya SYu, Peremot SD, Krivoruchko IA, Romanova MB, Rodchenko AA, Saydametov RR. Modern
aspects of ethyological role of Helicobacter pylori and some
representatives of Herpesviridae fam-ily in development of malignant
tumors of stomach are reviewed. The data from literature about
potential action of Helicobacter pylori during of development of
MALT-lymphoma and carcinoma of stomach and relation this pathol-ogy
with genetic profile of pathogenesis and his possible role in disorder
of optimal relationship of the processes of proliferation and apoptosis
are presented. The possible role of bacterial-viral association
(Helicobacter pylori-Herpesviridae) in induction of malignant
transformation of cells gastroduodenal zone and their mutual
potentially influence on this process is discussed.
Key words: Helicobacter pylori, Herpesviridae, tumors of stomach, apoptos, immunological mechanisms of defense |
48-65 |
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| ÍÎÂÛÉ ÊÎÐÎÍÀÂÈÐÓÑ – ÂÎÇÁÓÄÈÒÅËÜ ÀÒÈÏÈ×ÍÎÉ ÏÍÅÂÌÎÍÈÈ. Êîðîâàåâà È.Â., Âîâê Ñ.È., Ïàí÷åíêî Ë.À. THE NEW CORONAVIRUS – ETIOLOGIC AGENT OF ATYPICAL PNEUMONIA. Korovayeva IV, Vovk SI, Panchenko LA. The atypical
pneumonia, which is causing by new coronavirus, has been viewed in this
article. The data of etiology, epidemiology, clinic manifestation,
diagnostics, treatment and prophylaxis of disease has been description.
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66-74 |
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| ÂËÈßÍÈÅ ÏÐÎÖÅÑÑÀ ÒÐÀÍÑÊÐÈÏÖÈÈ ÍÀ ÎÁÐÀÇÎÂÀÍÈÅ ÄÂÎÉÍÛÕ ÐÀÇÐÛÂΠÏÐÈ ÂÛÑÎÊÎÌÎËÅÊÓËßÐÍÎÉ ÔÐÀÃÌÅÍÒÀÖÈÈ ÄÍÊ Êîëîòîâà Ò.Þ. ASSOCIATION BETWEEN TRANSCRIPTION AND DOUBLE-STRAND BREAKS FORMATION DURING HIGH MOLECULAR WEIGHT DNA FRAGMENTATION Kolotova T. Yu. In this
work the results of study of DNA cleavage into high molecular weight
fragments in murine thymocytes and human lymphoblastoma cells (line
CEM) have been summarised. It has been revealed the influence of
inhibitors of RNA and protein synthesis actinomycin D and cyclogeximid
on the high molecular weight DNA fragmentation. The inhibition of high
molecular weight fragmentation in thymocytes by actinomycin D confirmed
the supposition about the requirement of transcription for the DNA
disintegration. Moreover the distribution pattern of topological
domains containing c-myc between cleavable and uncleavable DNA fraction
in CEM cell during and after starvation reflects the transcriptional
activity of the gene.
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75-83 |
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| ÁÈÎËÎÃÈ×ÅÑÊÈÅ ÑÂÎÉÑÒÂÀ ØÈÃÅËË, ÈÇÎËÈÐÎÂÀÍÍÛÕ Â ÑÅÂÅÐÎ- ÂÎÑÒÎ×ÍÎÌ ÐÅÃÈÎÍÅ ÓÊÐÀÈÍÛ Â 1996-2003 ãã. Äüÿ÷åíêî À.Ã., Ðóäåíêî Ñ.Ñ., Ãàëóøêî Í.À., Áîæêî Ì.Ã., Äüÿ÷åíêî Ï.À., Ïàñå÷íèê Ò.Î. BIOLOGICAL PROPERTIES OF SHIGELLA SPP. ISOLATED IN SUMY REGION IN 1996-2003 Djachenko AG, Rudenko SS, Galuchko NA, Bogzko MG, Djachenko PA, Pasechnik TO. The
purpose of the study – to determine the sensitivity of Shigella sonnei
and Shigella flexneri to antimicrobial drugs and their clinical
effectiveness for moderating recommendations for empiric therapy of
shigellosis. A total of 164 strains of S.flexneri and 80 strains of
S.sonnei isolated in Sumy region of Ukraine during 1996-2003 years were
tested to 19 antimicrobials: ampicillin (Am), tetracyclin (Te),
rifampicine (Ri), chloramphenicol (Ca), streptomycin (St), fusidin
(Fu), êanamycin (Ên), erythromycin (Er), carbenicillin (Cb), doxicyclin
(Do), gentamycine (Ge), ofloxacin (Of), cefazolin (Cf), ciprofloxacin
(Cp). High rate of resistance were found in both S.flexneri and
S.sonnei to: Am (100%), Te (100%), Cb (90 and 50% respectively), Do (90
and 35% respectively), Fu (100%), Er (100%), Ri (100%), Ca (71,8 and
45% respectively), St (81 and 40% respectively). Some isolates were
resistant to ftorchinolones.
Key words: Shigella spp., sensitivity to antibiotics |
84-89 |
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| ÍÅÊÎÒÎÐÛÅ ÏÐÈ×ÈÍÛ ÔÎÐÌÈÐÎÂÀÍÈß ÄÈÑÁÀÊÒÅÐÈÎÇÀ ÊÈØÅ×ÍÈÊÀ Ó ÄÅÒÅÉ Â ÂÎÇÐÀÑÒÅ ÄÎ 3-Õ ËÅÒ Äåðêà÷ Ñ.À., Íîñàòåíêî À.È., Êðûëîâà È.À., Ñòðîãàÿ Å È., Äàâûäåíêî Ì.Á. SOME REASONS OF FORMATION INTESTINAL DYSBACTERIOSIS AT CHILDREN UNDER 3 AGE MECHNIKOV INSTITUTE OF MICROBIOLOGY AND IMMUNOLOGY OF UKRAINE MSA Derkach SA, Nosatenko AI, Krilova IA, Strogaya EI, Davidenko MB. The
reasons of formation dysbacteriosis’s formation at 160 children under 3
age were investigated. Such factors as alimentary diarrheae, colitises;
allergic diseases (diathesises, dermatiteses); eating of motherly milk,
physiological labor or delivery by cesarean section were taken into
account. Anamnestic data and results of bacteriological examination
were analyzed. It was established that at 61,1 - 88,6 % of children
after delivery by cesarean section and eating of motherly milk less 25
days had significant quantitative and qualitative changes in the
content of intestinal microflora. The principal disorders were:
decrease of bifidum and lactobacteria (< 1x107 CFU/g); bacterial
contamination; colonization of enterobacteria, pathogenic
staphylococcus wither hemolytic properties, fungi of Candida genus.
Intestinal dysbacteriosis was registrated more often at children with
allergic diseases and with functional disorder of intestinal tract
(33,3 % and 62,5 % of total number of examinated children,
respectively. Such children consist the group of risk, which needs in
examination of intestinal microflora to determine the complex approach
to treatment and choice of optimal probiotics.
Key words: dysbacteriosis, intestinal microflora, probiotics, eubiotics, bacteriophages, sorbents. |
90-99 |
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| ÍÈÊÎËÀÉ
ÍÈÊÎËÀÅÂÈ× ÁËÀÃÎÂÅÙÅÍÑÊÈÉ – ÎÐÃÀÍÈÇÀÒÎÐ È ÏÅÐÂÛÉ ÐÓÊÎÂÎÄÈÒÅËÜ ÊÀÔÅÄÐÛ
ÌÈÊÐÎÁÈÎËÎÃÈÈ ÄÎÍÅÖÊÎÃÎ ÃÎÑÓÄÀÐÑÒÂÅÍÍÎÃÎ ÌÅÄÈÖÈÍÑÊÎÃÎ ÓÍÈÂÅÐÑÈÒÅÒÀ (Ê
110-É ÃÎÄÎÂÙÈÍÅ ÑÎ ÄÍß ÐÎÆÄÅÍÈß) Íèêîëåíêî Þ.È., Æàäèíñêèé Í.Â., Åëüñêèé Â.Í., Áëàãîâåùåíñêàÿ Í.È. , Åëüñêèé Â.Í. |
83-105 |
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