Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
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Çì³ñò (Contents) |
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ÎÃËßÄÈ (REVIEWS) |
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| ÅÔÅÊÒÈÂͲÑÒÜ ÒÀ ²ÄÏβÄͲÑÒÜ Ã²Ã²ªÍ²×ÍÈÌ ÂÈÌÎÃÀÌ Ô²ÇÈÊÎ-ղ̲×ÍÈÕ ÑÏÎÑÎÁ²Â ÇÍÅÇÀÐÀÆÓÂÀÍÍß ÂÎÄÈ (ÎÃËßÄ Ë²ÒÅÐÀÒÓÐÈ) Õ³ðíà Ò.Â. THE EFFECTIVENESS AND ACCORDANCE OF PHYSICOCHEMICAL WAYS OF DISINFECTION OF THE WATER WITH HYGIENIC DEMANDS Hernaya T.V. The
problem of disinfection of the water is getting more topicality because
of the abrupt worsening of the ecology situation. The analysis of the
information of scientific literature, which is presented in the review,
characterizes modern ways of disinfection of the water with the help of
chemical, physical and combined factors. The methods of disinfection
are characterized from the positive way of the effectiveness of an
antimicrobial action and from the negative way of different ways of
processing the water.
Key words: disinfection of the water, chlorination, ozone treatment, combined methods. |
1-11 |
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| Î ÐÎËÈ ËÀÒÅÍÒÍÛÕ, ÒÐÓÄÍÎ ÊÓËÜÒÈÂÈÐÓÅÌÛÕ È ÍÅÊÓËÜÒÈÂÈÐÓÅÌÛÕ ÏÅÐÑÈÑÒÅÍÒÍÛÕ ÁÀÊÒÅÐÈÉ Â ÏÀÒÎËÎÃÈÈ ×ÅËÎÂÅÊÀ Åëèñååâà È.Â., Áàáè÷ Å.Ì., Âîëÿíñêèé Þ.Ë., Ñêëÿð Í.È., Áåëîçåðñêèé Â.È. A ROLE OF LATENT, DIFFICULTLY CULTIVATED OR NON-CULTIVATED PERSISTENT BACTERIA IN HUMAN PATHOLOGY Yelyseyeva I., Babich Ye., Volyansky Yu., Sklyar N., Bilozersky V.I. The
purpose of this literature review is a consideration of a role of
bacteria L-forms in human pathology. It was presented biological
characteristic of L-forms, their induction’s conditions, culture
properties, morphology, phases of bacteria’s conversion in L-forms and
reversion to parent bacteria; it was shown metabolic activity of
L-forms, capacity for survival during the phagocytosis and antigenic,
immunogenic and sensitizing abilities. L-forms’ pathogenic potency were
summarized according to the experimental data in vitro and in vivo, as
well as clinical facts about different infectious human illnesses,
autoimmune diseases and pathology with unestablished etiology. Some
theoretic and practice questions about bacteria L-forms which require a
further investigations are listed.
Key words: bacteria L-forms, biological properties, phagocytosis, antigenicity, immunizing capacity, etiology of diseases. |
12-46 |
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| ËÀÒÅÍÒÍÀ ²ÍÔÅÊÖ²ß ßÊ ÔÀÊÒÎÐ ÐÈÇÈÊÓ ØÂÈÄÊÎÃÎ ÏÐÎÃÐÅÑÓÂÀÍÍß ÀÒÅÐÎÑÊËÅÐÎÒÈ×ÍÎÃÎ ÏÐÎÖÅÑÓ Êðåñòåöüêà Ñ.Ë., Êðåñòåöüêèé Ì.Ã., Âîëÿíñüêèé À.Þ., Êîëÿäà Î.Ì., Êàçì³ð÷óê Â.Â. LATENT INFECTION AS A RISK FACTOR FOR ATHEROSCLEROSIS FAST PROGRESSION Krestetska S.L., Krestetsky M.G., Voliansky A.U., Koliada O.N., Kazmirchuk V.V. A decade
ago, the correction of hypercholesterolemia and hypertension was
expected to prevent the fast progressing of atherosclerotic process
and, in an essential measure, to warn occurrence of critical vascular
events. But now, àn increasing body of evidence suggests that existing
conventional risk factors such as hypertension, hyperlipidaemia,
diabetes mellitus and smoking account for only about 50% of
atherosclerosis clinical occurrence. This fact proves expediency of new
search for reliable influence factors and estimation its risks value.
The infectious hypothesis proposes that various microorganisms may
serve as potential etiological factors, linking inflammation and
atherosclerosis (or its clinical manifestations, which now is the
leading cause of critical vascular events). Evidence from
seroepidemiology, molecular biology, immunology, pathology, animal
models and human antibiotic intervention studies, collectively have
suggested a largely positive association between infection and
atherosclerosis. However, the precise nature of a causal or
coincidental link between infection and atherosclerosis remains to be
determined. A current perspective is presented in this review.
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47-65 |
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| ÄÎÇÎÐÍÛÉ
ÝÏÈÄÅÌÈÎËÎÃÈ×ÅÑÊÈÉ ÍÀÄÇÎÐ ÇÀ ÂÈ×-ÈÍÔÅÊÖÈÅÉ ÑÐÅÄÈ ÁÎËÜÍÛÕ Ñ
ÇÀÁÎËÅÂÀÍÈßÌÈ, ÏÅÐÅÄÀÞÙÈÌÈÑß ÏÎËÎÂÛÌ ÏÓÒÅÌ. ÎÖÅÍÊÀ ÐÀÑÏÐÎÑÒÐÀÍÅÍÍÎÑÒÈ
ÈÍÔÅÊÖÈÈ Ïîçäíÿêîâ Ñ.Â., Ëåáåäþê Ì.Í., Ôó÷èæè È.Ñ., Ñëàâèíà Í.Ã., Ïîïîâà Þ.À., Ìàðãîëèíà Î.Í. SENTINEL SURVEILLANCE ON HIV-INFECTION IN PATIENTS WITH SEXUALLY TRANSMITTED DISEASES (STD). EVALUATION OF THE DISTRIBUTION Pozdnyakov S.V., Lebedyuk M.N., Fuchigy I.S, Slavina N.G., Popova J.A., Margolin O.N. Evaluation
of the HIV-infection distribution in the population of the South region
of the Ukraine (northern-west Black Sea costal region) with use of the
standard information forms and results of the sentinel surveillance in
group of the STDs pa-tients was done. HIV antibodies were detected in
40 samples of the 858 collected. Prevalence rate - 4,66% ± 0,72%, a
little bit higher than obtained by the standard seromonitoring
(3,74±0,35%). Conclusion is as follows - sentinel surveillance method
allows obtain results characterizing prevalence level of the
HIV-infection in the target group, which are not worth the standard
seromonitoring results. For the monitoring of the situation in the
target group, it will be necessary to continue investigations in the
same periods
Key words: HIV-infection, HIV/AIDS, STD, infection distribution. |
66-72 |
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| ÄÎÇÎÐÍÛÉ
ÝÏÈÄÅÌÈÎËÎÃÈ×ÅÑÊÈÉ ÍÀÄÇÎÐ ÇÀ ÂÈ×-ÈÍÔÅÊÖÈÅÉ ÑÐÅÄÈ ÁÎËÜÍÛÕ Ñ
ÇÀÁÎËÅÂÀÍÈßÌÈ, ÏÅÐÅÄÀÞÙÈÌÈÑß ÏÎËÎÂÛÌ ÏÓÒÅÌ. ÎÖÅÍÊÀ ÐÈÑÊÎÂÀÍÍÛÕ ÔÎÐÌ
ÏÎÂÅÄÅÍÈß, ÂËÈßÞÙÈÕ ÍÀ ÐÀÑÏÐÎÑÒÐÀÍÅÍÈÅ ÈÍÔÅÊÖÈÈ Ïîçäíÿêîâ Ñ.Â., Ëåáåäþê Ì.Í., Ôó÷èæè È.Ñ., Ñëàâèíà Í.Ã., Ïîïîâà Þ.À., Ìàðãîëèíà Î.Í. SENTINEL SURVEILLANCE CONTROL ON HIV-INFECTION IN PATIENTS WITH SEXUALLY TRANSMITTED DISEASES. EVALUATION OF THE BEHAVIORAL RISK MODELS INFLUENCING HIV-INFECTION DISTRIBUTION Pozdnyakov S.V., Lebedyuk M.N., Fuchigy I.S., Slavina N.G., Popova J.A., Margolin O.N. Evaluation
of the behavioral risk models influencing HIV-infection distribution,
subjective and objective consideration to the risk group and level of
the AIDS issues information were done in the frames of the sentinel
surveillance control (SSC). For the processing and evaluation of the
respondent’s anonymous polling data, personal computer program was
used. It was marked ssignificant part of the STDs patients which are at
the risk zone, includ-ing drug abuse. At the same time, level of the
complex AIDS issues conversance is low, wile subjective opinion value
added. Disbelief in possible turn for the safe behavior in 40% of
polled shows potential threat of the STDs patients for the further
infection distribution in the marked group and ordinary population
through the sexual contacts. Use of the effective informational and
educational programs for the patients with STDs is needed as well as
constant SSC for the control of the situation.
Key words: AIDS, SSC, STD, risk behavior |
73-78 |
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| ÀÍÒÈ̲ÊÐÎÁͲ ÒÀ ÏÐÎÒÈÃÐÈÁÊβ ÂËÀÑÒÈÂÎÑÒ² ÑÓÊÖÈÍÈËÜÎÂÀÍÎÃÎ β-ÖÈÊËÎÄÅÊÑÒÐÈÍÓ ² ÉÎÃÎ ÊÎÌÏËÅÊÑÓ ÂÊËÞ×ÅÍÍß Ç Í²ÑÒÀÒÈÍÎÌ Ìàðòèíîâ À.Â., Êëåì÷óê Ë.Â., Îñîëîä÷åíêî Ò.Ï., Áàòðàê Î.Î., Ïåòðîâà Ò.Ì., Øòèêåð Ë.Ã., Çàâàäà Í.Ï., ˳ñíÿê Þ.Â. ANTIMICROBIAL AND ANTIFUNGAL PROPERTIES OF SUCCINYLATED β-CYCLODEXTRIN AND ITS INCLUSION COMPLEX WITH NYSTATIN Martynov A.V., Klemchuk L.V., Osolodchenko T.P., Batrak E.A., Petrova T.M., Shtyker L.G., Zavada N.P., Lisnyak Yu.V. In the
paper, results of studies on antimicrobial and antifungal properties of
succinylated β-cyclodextrin and its inclusion complex with nystatin are
presented. It is shown that β-cyclodextrin does not form inclusion
complex with nystatin whereas succinylated β-cyclodextrin forms
opalescent inclusion complex with nystatin. Mass of the inclusion
complex determined by gel-electrophoresis differs considerably from the
calculated one. It may be caused by the more rigid structure of
inclusion complex and correspondingly by decrease of its mobility in
the gel. It is shown that succinyl β-cyclodextrin has apparent activity
against P.aeruginosa, C.albicans and A.niger and strong one against
S.aureus whereas in accordance with literature non-acylated
β-cyclodextrin has no antimicrobial and antifungal properties.
Inclusion complexes between succinyl β-cyclodextrin and nystatin were
more active (by 15%-30%) compared to nystatin and β-cyclodextrin taken
separately.
Key words: β-cyclodextrin, succinyl β-cyclodextrins, nystatin, inclusion complex, antimicrobial and antifungal properties |
79-84 |
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| ÂÊËÀÄ Â.Ê. ÂÛÑÎÊÎÂÈ×À  ÐÀÇÂÈÒÈÅ Ó×ÅÍÈß ÎÁ ÈÍÔÅÊÖÈÎÍÍÛÕ ÁÎËÅÇÍßÕ Ïóãà÷ Í.Á. CONTRIBUTION OF V.K. VISOKOVICH INTO DEVELOPMENT OF
STUDIES ABOUT INFECTIOUS DISEASE In the article the author pays attention
to the number of important sides of activity of genius microbiologist V.K.
Visokovich; reveals fundamental principles and hypotheses of new immunity
theory; investigates stages of scientific methods in creation of absolutely new
type of vaccine getting from killed culture and shows mechanism of their
actions against infectious disease including antrax. The author lays stress on
the role of I.I. Mechnikov and V.K. Visokovich in
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85-94 |
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