Annals of Mechnikov's Institute 2007 1
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Contents)



C. (P.)


(Editorial Board)

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(Contents)

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(REVIEWS)



βֲ ֲ: ͲͲ ̲ ֲ
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AUTOINDUCTION AND SIGNAL TRANSDUCTION: COMMUNICATION SYSTEMS IN MICROBIAL POPULATIONS
Krestetska S.L., Nesterenko A.M
The discovery of intercellular communication mechanisms in bacterial populations has shaken the conception of eukaryotic autonomous existence, according to which it was considered that the spectrum of information, that is available for perception in microorganisms is restricted to exogenous signals, concern only the surrounding conditions for existence (in particular, availability of plastic and energetic resources, , temperature, and so on). More than 30 years ago the ability of bacterialal population to coordinate their behavior was discovered. At present in many species various mechanisms of production, reception and utilization of signal information for regulation of expression of certain genetic complexes were described. The existence of interspecies signal interference was demonstrated. Moreover, it was shown that in evolution process these very mechanisms were used for signal information perception and utilization in multicellular organisms, which allows speaking about existence of principally new level of adaptation behavior regulation in microbial populations. We call your attention to a short review of general theses and separate trends of research in the field that is considered for good reason to be the sphere of the most dynamic development in modern microbiology.
Kay words: quorum sensing; autoinducer; cell-to-cell signalling.

4-9

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HORMONAL BRANCH OF IMMUNOSUPPRESSION MECHANISM
Volyansky A.J., Symyrenko L.L., Stetsenko V.I., Kuchma I.J.
The hormonal reactivity of hypophysis-thyroid gland system and glucocorticoid hormones of hypothalamo-hypophyso-adrenocortical system in immunization of rabbits with a bovine diarrhea virus strain Oregon With - 24V(BDV) was studied. The examined systems are involved in mecha-nism of the immunosupression influence of BDV on the organism. This indicates that these systems can be used for an early estimation of virus strains immunogenicity level in the new vaccine preparation development.
Key words: ortisol, thyroid hormones, immunogenesis

10-12

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Ҳ IJ Ͳ (1990-2004 )
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PECULARITIES OF LICE INFESTATION AMONG CHILDREN IN UKRAINE (1990-2004)
Kurhanova I.I., Kicara M.S., Murzova L.I., Balackli-ets T.I., Ponomareva N.V.
The general tendency for decreasing the lice infestation both among all the population and the children under 14 was found. The level of the childrens infestation was higher than that of the adults. The head lice infestation predominated over the body and mixed lice infestation. The highest infestation was among children of the age groups 7-14 years old and in such social groups as the schoolchildren in the boarding schools and the children who didnt attend any kindergarten. The body and mixed lice infestation occur more frequently in these groups as compared with other groups of children too. Lice infestation preserkes its epidemiological significance as the vector of the causative agent of trench fever. It has the negative influence on the current epidemiological situation in the state.
Key words: zice, the infestation, the heed lice, the body lice, the children, rickettsiacarrying.

13-18

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˲ IJ A.VRDANS 167 Ͳ ˲
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RESEARCH ACTION OF PROBIOTICS CULTURE OF A.VRDANS INTERTWINED CULTURES OF CELLS
Ryzhenko S., Kremenchutskiy G., Bredhna ., Kovalenko S.
Information is presented about the cytopathic effect of probiotics culture of Aerococcus viridans N 167 on the in tissue culture of Hep-2, RD and L-41. Cytopathic stability in tissue culture of Hep-2 is set to A.viridans in conctntration 610 5 CGU/ml.
Keywords: cytopathic effect, intertwined cultures of cells, Aerococcus viridans N 167

19-22

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Ͳ ̲ .VIRIDANS ²в
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ANTAGONISTIC INFLUENCING OF CULTURES .VRDANS ON VIBRIOS
Ryzhenko S., Drobot E.
In work the mutual relations of Àerococcus viridans are investigational with V.parahaemolyticus, V.alginlyticus and V. cholerae non 1. Antagonistic activity is set A.viridans in regard to V.parahaemolyticus, V.alginlyticus and V.cholerae non 1. Different oxidase and antagonistic activity of cultures A.viridans testifies to the additional bactericidal factors which need further study.
Keywords: erococcus viridans, V.parahaemolyticus, V.alginlyticus, V. cholerae non 1, antagonism
 

23-24

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THE MICROBIOCENOS OF LARYNGO-PHARYNX OF PATIENTS WITH ACUTE EPIGLOTTITIS
POPOV N. N., SAVCHENKO A.V., VISEKANTSEV I.P.
The microbiological inspection of 70 patients with acute epiglottitis displayed, that microbial flora of mucous membrane of epiglottis includes a lot of pathogenic and opportunistic bacterias, which belong to different taxons and also funguses C. albicans. The evolution of catarrhal and necrotic forms of acute epiglottitis doesn't depend on specific composition of microbial flora and extent of contamination of mucous membrane of epiglottis.
Key words: acute epiglottitis, microbial flora
 

25-29

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̲òί IJ ί ֲ
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IMPROVEMENT OF NUTRIENT MEDIA FOR MICROBIOLOGICAL DIAGNOSTICS OF BAR-TONELLA INFECTION
Pokhil S.I., Bondarenko E.V., Timchenko E.N. and Bondarenko A.V.
To improve nutrient media for the more rapid isolation and growth of Bartonella spp. strains there was studied the stimulating effect on them of number of ingredients: hemine (HEM); stimulator of plague microbe growth (SPMG); mixture of the products of enzyme hydrolysis of yeast (MPEHY); growth stimulating mixture consisting of dipyrimidyl pyrimidine (tertamethoxy)-ethicanine, tetraethyl-tetramethoxy-phenyl-iso-quinoline, phenylmethylbenz-imidazole (DPD). It was found that the character and degree of stimulating effect of studied ingredients on growth of Bartonella spp. strains is determined by type of the stimulator and its concentration in medium.
Key words: Bartonella, nutrient media, growth stimulators, macrocolonies


30-37

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DEVELOPMENT AND LABORATORY SCALING OF SOME ANTIMICROBIAL PREPARATIONS AND ANTIBIOTICS
Guk I.A., Bocharova I.A., Dil A.D. Asmolova N.N., Shteyngart M.V.
Technology of core tablets based on study antimicrobial drugs of Levofloxacine hemihydrate and Claritromicine technological behaviour was conducted by wetting granu-lating with polymer granulated excipients. The release being insensitive to variations in the pH of the dissolution medium can be obtain thanks to district maintenance of wet granulation conditions both in mortar as in pilot equipment. The main technological conditions what can change in scale up are conditions of blending, the tem-perature of product, time of drying. The choice of mois-turizer concentration determines the difference of tablet mass behavior during wetting and influence on techno-logical behavior of mass.
Key words : Levofloxacine, Claritromicine, technology, granulation.
38-41

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