Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-4 |
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ÎÃËßÄÈ (REVIEWS) |
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̲ÊÐÎÔËÎÐÀ ϲÕÂÈ Ó Æ²ÍÎÊ ÐÅÏÐÎÄÓÊÒÈÂÍÎÃΠ²ÊÓ Â ÍÎÐ̲ ² ÏÐÈ Ð²ÇÍ²É ÏÀÒÎËÎò¯ Âîëêîâ Ò.À., Áîëüøàêîâà Ã.Ì. THE VAGINAL MIKROFLORA OF REPRODACTIVE AGE`S WOMEN IN THE NORM AND AT DIFFERENT PATOLOGIC PROCESSES. LITERARY REVIEW Volkov T.A., Bolshakova G.M. The data
ofscientific literature, concerning the vaginal microflora of
reproductive age women in the norm and different patalogic processes:
bacterial vaginosis, clamidiosis, ureaplasmosis,
mycoplasmosis, urogenital candidosis and
nonspecific inflammatory processes urogenital tract.
Key words: vaginal normal microflora, bacterial vaginosis, trichomoniasis, clamidiosis, aerobic and anaerobic microorganisms. |
5-13 |
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| ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ
ÐÎÁÎÒÈ (EXPERIMENTAL STUDY) |
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| ANTIMICROBIAL
ACTIVITY OF SYNTHETIC DERIVATES OF CONDENSED
HETEROCYCLIC COMPOUNDS WITH PYRIDINE FRAGMENT Evsukova V.Y., Andreieva I.D., Kazmirchuk V.V., Shulga N.M., Shcherbak O.M., Yuchimenko V.I.. An
experimental study of the level and
range of antimicrobial activity was carried out among the
synthetic derivates of condensed heterocyclic
compounds with pyridine fragment. A hign
antimicrobial activity of the studied
compounds against gram-negative (Escherichia
coli ÀÅÑÑ 25922) and gram-positive
(Staphylococcus àureus ÀÒÑÑ 25923, Bacillus anthracoides
ÀÒÑÑ 1312) bacteria was proved. The
experimental data have proven the perspectivity of the
further research of the range and level of antimicrobial activity of
the compounds chosen in the course of primary screening
against the reference strains pathogens of
infectious and purulent-inflammatory diseases.
Key words: microorganisms, condensed heterocyclic compounds, antimicrobial activity , infectious and purulent inflammatory diseases. |
14-18 |
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| FEATURES
OF IMMUNE STATUS AT PATIENTS BY
ACUITY CORONAL SYNDROME UNDER HERPESVIRUS PERSISTENCE Peremot S.D., Smelyanskaya M.V., Martynov A.V., Peremot Y.A. The immune
status of the patients by ischemic heart diseases is characterized by
deficiency of T-cells part of immune system, appearance of functionly
incomplete T lymphocytes, and also some
changes of humoral immune responses. The
interrelation between a T-lymphopenia and fact herpesviral
persistence for patients with various
forms of IHD is taped, that specifies formation of a set of
secondary immunodeficiency symptoms, which can be regarded as result of
long herpesviral persistence and exhibiting of a chronic intravascular
inflammation, pathogenetical linked with an atherosclerosis.
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19-23 |
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| ÑÈÍÒÅÇ
ÄÂÓÕÌÅÐÍÛÕ ÌÅÌÁÐÀÍ ÍÀÍÎÐÀÇÌÅÐÍÛÕ ÏÎ ÒÐÅÒÜÅÉ ÊÎÎÐÄÈÍÀÒÅ ÈÇ ÁÈÎËÎÃÈ×ÅÑÊÈ
ÀÊÒÈÂÍÛÕ ÔÐÀÃÌÅÍÒΠF(ab`)2 FITCÈ ÈÑÑËÅÄÎÂÀÍÈÅ ÈÕ ÁÈÎÑÅÍÑÎÐÍÛÕ ÑÂÎÉÑÒ Äæåëàëè Â.Â., Âîëÿíñêèé À.Þ., Ãëàçóíîâà Ë.È., Ìàðòûíîâ À.Â., Îñîëîä÷åíêî Ò.Ï., Êëåì÷óê Ë.Â. SYNTHESIS OF THE TWO-DIMENSIONAL MEMBRANES NANOSIZED ON THE THIRD COORDINATE FROM BIOLOGICALLY ACTIVE FRAGMENTS OF F (AB `) 2FITC AND THEIR BIOSENSOR PROPERTIES RESEARCH Dzhelali V.V., Voljanskij A.J., Glazunova L.I., Martynov A.V., Osolodchenko T.P., Klemchuk L.V. In the
present work study a method of synthesis is of 20 layer film from
anti-mice IgG sheep antibodies F (ab `) 2FITC 40 - 80 nm thick on the
Pt electrode surface is proposed. At the potentials lower than - 0,250
V a cationconductance channels are opened in the obtained membrane,
at the potentials higher than 0,200 V anionconductance channels are
being opened. In the range between -0,250 and 0,200 V the conductance
of this membrane is stochastic fluctuates. Stochastic fluctuations of
conductance of membrane and current through membrane
are determined by the stochastic fluctuations of the number open of ion
conductance channels. On the basis voltampere measurements it was shown
that at the cathodic potentials lower than -0,250 V it carries out a
function of organic ionselectiv membrane for the mice blood
serum antigens. According to the hronoamperegrames taken off -0,280 V
the studied interphase border Pt/nanomembrane F (ab `) 2 FITC/NaÑl -
0,3 M + Na2ÍÐÎ4- 0,05 M is a bioelectrochemical sensor for added to the
electrolyte solution mice blood serum antigens and allows selective
registration of the former.
Key words: synthesis, membrane, biosensor, antigen |
24-31 |
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| ²ÌÓÍÎÌÎÄÓËÞÞ×À Ä²ß Ë²ÏÎÏÎ˲ÑÀÕÀÐÈIJ BACILUS ALVEI
Âîëÿíñüêèé À.Þ. IMMUNOMODULATION ACTION OF LIPOPOLYSACCHARIDES FROM BACILLUS ALVEI Volaynskiy A.U. The
results of study in vitro of influence lipopolysaccharides from
Bacillus alvei on functional activity macrophages and their
predecessors are submitted. The immunomodulating peculiarities of
lipopolysaccharides from 3 strains of Bacillus alvei have been studied.
The results of researches confirm prospect of use lipopolysaccaride..
from Bacillus alvei for immunomodulation.
Key words: lipopolysaccharides from Bacillus alvei, immunomodulation, immunocompetent cells, Bacillus alvei. |
32-34 |
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| ÃÎÐÌÎÍÀËÜÍÈÉ ÑÒÀÍ ÙÓв ÇÀ ÓÌΠ²ÌÓͲÇÀÖ²¯ ÍÀ Ò˲ ÅÊÑÏÅÐÈÌÅÍÒÀËÜÍÎÃΠòÏÎÒÈÐÅÎÇÓ Êó÷ìà ².Þ., Ñèìèðåíêî Ë.Ë., Íèêèò÷åíêî Þ.Â., Âîëÿíñüêèé À.Þ., Öåéòë³í Í.À. THE HORMONAL STATUS OF RATS AT IMMUNIZATION ON THE BACKGROUND OF EXPERIMENTAL HYPOTHYROIDISM Kuchma I.J., Simirenko L.L., Nikitchenko J.V.,bVoljanskij A.J., Tsejtlin N.A. The
features of immunogenesis hormonal regulation at rats
immunization on the background of experimental
hypothyroidism induced by introduction
1-metil-2-merkaptoimidazol are studied. The dynamics of changes
of blood whey thyroid hormones
concentrations at hypothyroid
rats in the course of formation
of the postvaccinal humoral immune answer on ADT-anatoxin are
described by empirical regression functions.
Keywords: thyroid hormones, hypothyroidism, imunization, humoral immune answer, corticosteron |
35-38 |
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| ÂÏËÈÂ
ÑÏÎËÓÊ Ç ÐßÄÓ ²Ì²ÄÀÇÎ[2,1-b]Ò²ÀÇÎ˲ ÍÀ
ÏÎÊÀÇÍÈÊÈ ²ÌÓÍÎËÎò×Íί ÐÅÇÈÑÒÅÍÒÍÎÑÒ²  ÓÌÎÂÀÕ
IN VITRO Êîçàð Â. Â., Êóäðÿ Ì. ß.,. Ïàâëåíêî Ò. Î, Ñîâà Î.Ì., ßðåìåíêî Ô. Ã INFLUENCE OF COMPAUNDS SERIES IMIDAZO [2,1-b]TIAZOLES ON THE IMMUNE RESISTANCE INDEXES IN VITRO Kozar V. V., Kudrya M. Y., Pavlenko T. O, Sova O.M., Yaremenko F. G. The
influence of levamisole and its
derivative on the cellular, on the
phagocyte link of immunity, on the
leukocytes` migration faculty in the conditions in vitro has been
studied. It has been revealed that the compounds are similar
in action towards T- and B-lymphocytes, metabolic
and phagocyte activity of
leucocytes. The difference is that
the levamisole derivative is more
efficient in stimulating the absorbent
faculty of granulocytes, and levamisole
in stimulating migration activity of leucocytes.
Key words: levamisol, levamisole derivative, Tlymphocytes, B-lymphocytes, phagocytosis, migrantion activity of leucocytes. |
39-42 |
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| ÏÎвÂÍßËÜÍÀ
ÕÀÐÀÊÒÅÐÈÑÒÈÊÀ ×ÓÒËÈÂÎÑÒ² ̲ÊÐÎÎÐÃÀͲÇ̲Â, ÂÈËÓ×ÅÍÈÕ
Â²Ä ÕÂÎÐÈÕ Ä²ÒÅÉ ÄÎ ÏÐÅÏÀÐÀҲ - ÁÀÊÒÅвÎÔÀò Äåðêà÷ Ñ.À., Êîöàð Î.Â., Âîðîíê³íà ².À., Ãàáèøåâà Ë.Ñ., Êîðîáêîâà ².Â. COMPARATIVE CHARACTERISTIC OF GERMS SENSITIVE EXUDED FROM DISEASED CHILDREN TO ACTION FROM COMMERCIAL SERIES BACTERIOPHAGIES MEDICINES Derkach S.A.,Kotsar E.V.,Voronkina ².À., Gabisheva L.S.,Korobkova I.V. Comparison
of study phagosense of stains exuded from different epitops from
diseased children to action from commercial series of bacteriophagies
medicines. It had been stated that in owerage 50-70% circulate stains
were phagosensetive.
Key words: phagoterapia, bacteriophagies, phage susceptibility. |
43-47 |
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| ÂËÈßÍÈÅ ÆÈÄÊÈÕ ÑÐÅÄÑÒ ÃÈÃÈÅÍÛ ÍÀ ÑÎÑÒÎßÍÈÅ ÌÈÊÐÎÔËÎÐÛ ÇÓÁÍÎÃÎ ÍÀËÅÒÀ Äîíöîâà Ä.À., Ðÿáîêîíü Å.Í., Îñîëîä÷åíêî Ò.Ï., Øòèêåð Ë.Ã. INFLUENCE OF LIQUID MEANS OF HYGIENE OF AN ORAL CAVITY ON STRUCTURE OF MICROFLORA OF A TOOTH TOUCH Dontsova D.O., Ryabokon Y.M., Osolodchenko T.P., Shteeker L.G. In work
results of researches of specific structure of microorganisms of a
tooth touch at group of students of medical university are given.
Studying of influence of liquid means of hygiene of an oral cavity on
change of structure of microflora is
spent. The received results specify
in necessity of the control from
outside the stomatologist of preventive application of
mouthwashes.
Key words: microflora, mouthwashes, tooth touch |
48-52 |
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| ÄÈÀÃÍÎÑÒÈÊÀ ÑÌÅØÀÍÍÛÕ ÈÍÔÅÊÖÈÉ Ó ÀÌÁÓËÀÒÎÐÍÛÕ ÁÎËÜÍÛÕ Ñ ÏÎÐÀÆÅÍÈÅÌ ÓÐÎÃÅÍÈÒÀËÜÍÎÃÎ ÒÐÀÊÒÀ Ïèëþãèí Ñ.Â., Êàçìèð÷óê Â.Â., Òîðÿíèê È.È. DIAGNOSTIC OF THE MIXT- INFECTIONS IN AMBULATORY PATIENTS WITH THE DISORDERS OF THE UROGENITAL TRACT Pilugin S.V., Kazmirchuk V.V., Torianik I.I. Diagnostic
of mixt-infections in the out-patients with the damage of the
urogenital tract is presented in the study. It was established that at
21,8% of ambulatory patients investigated mixt- urogenital infection
with a such dominated factor as a herpes simplex virus in a microbiotic
assotiation. The increasing of the illness and infectiousness of
ambulatory sick with the mono- and mixt herpesviral infection
may to determine the seature of
the biological property. For the increase
of the overt favorable longterm treatment
effect patients are needs in a
complex clinico-laboratory examination.
Key words:diagnostic, mixt-infections, out-patients, urogenital tract |
53-56 |
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| ÍÅÊÎÒÎÐÛÅ ÌÅÕÀÍÈÇÌÛ ÔÎÐÌÎËÜÍÎÉ ÄÅÒÎÊÑÈÊÀÖÈÈ ÑÒÎËÁÍß×ÍÎÃÎ ÒÎÊÑÈÍÀ Êàøïóð Í.Â., Âîëÿíñüêà Í.Ï., ×åðíÿâñêèé Â.È., Âîëÿíñêèé À.Þ., Ìàðòûíîâ À.Â. SOME MECHANISMS OF FORMOL DETOKSICATION OF TETANIC TOXIN Kashpur N.V., Chernajvsky V. I., VolyanskyN.P., Volyansky A. Yu, Martynov A.V. A tetanus
is widely enough widespread in many countries of the world. Unflagging
interest to him is explained many reasons among which main is
ever-higher lethality. A vaccination is the unique effective method of
warning of tetanus. A basic task is an increase of adjuvanticity of producible
vaccines. Every stage of industrial receipt, cleaning and defusing of
toxin is exposed to the improvement to that end. A large value has
quality of nourishing environment and condition of cultivation.
Keywords: tetanus, toxin, toxoid, defusing. |
57-62 |
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