Annals of Mechnikov's Institute 2010 1
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Contents)



C. (P.)


(Editorial Board)

1

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(Contents)

3-4

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(REVIEWS)



THE ANTIBACTERIAL PROPERTIES OF CONDENSED HETEROCYCLIC COMPOUNDS
Evsukova V.Y., Andreieva I.D., Kazmirchuk V.V, slyanchuk ..
The review summarizes the data of domestic and foreign sources concerning antibacterial properties of condensed heterocyclic compounds of different groups. The prospect of direct synthesis of condensed heterocyclic compounds and the study of their antimicrobial activities in order to develop antibacterial agents on their basis is founded.


5-9

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PERSPECTIVES OF THE USING OF FULLEREN - CONSIST RAW MATERIALS IN MEDICAL AND PHARMACEUTICAL PRACTICE
Konyukhov I.V.
The natural mineral shungits using level for human needs, and also prospect of its use in medicine and pharmacy.

11-14

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IMMUNOLOGICAL DISBALANCE AT PATIENTS WITH ACUTE CORONARY SYNDROME IN THE CONDITIONS OF HERPETIC PERSISTENTION
Peremot S., Smelyanskaya ., Volyanskiy ., Romanova ., Peremot Y., Martynov .
The purpose of work was a study and estimation of influencing of features of virus induced of immunological disbalance on the case of ischemic heart trouble, developing on a background persisting herpetic infection. Were inspected 41 patient with ishemic heart disease, 20 patients with a acute coronary syndrome and 21 stable stenocardia, comparable on a sex and age. It is set that virus induced an immunological disbalance is foundation of destabilization of stream of ishemic  heart disease with forming of sharp coronary syndrome and characterized oppressing of functional activity of cellular link of immunity and increase of level circulating immune complexes with forming of hyperimmune syndrome and decreasing of level of general complement.

15-18

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(EXPERIMENTAL STUDY)



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THE RESEARCH OF BIOLOGICAL PARTICULARITIES OF CHLAMYDIAE ISOLATES, WHICH ISOLATED FROM DIFFERENT DESTRUCTION FOCUSES
Dzhoraeva S.K
It was presented the data of the electron microscopy and molecularbiological researches of chlamydiae, which isolated from different destruction focuses in cell culture system at the article. It has been established, that agents are distinguished by morphology, cultivation condition and are applied to different species. The realized investigations are demonstrated the possibility of the C. trachomatis gematogenic dissemination for development of the Reiters disease and the interrelation between the C. pneumoniae and pathogenic of atherosclerosis.


19-23

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ESHERICHIA COLI
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DRUG-RESISTANCE TYPES OF CLINICAL STRAINS ESHERICHIA COLI AND THEIR SAFETY IN THE CONDITIONS OF LOW TEMPERATURE STORAGE
Panasenko J.V., Birukova S.V.
The sensitiveness was studied to the antibiotics in clinical strains E. coli from different places. Fluoroquinolones (sensitiveness within the limits of 69,2-78,3%) and amikacin (72,5%) were appeared most effective. The strains without antibiotics R-determinants were absent, the maximal amount of R-determinants was 15. Storage at the ultra low temperature of liquid nitrogen during one year after cooling even with different programs provided not only safety of viability but also types of drug-resistance, that allows to recommend cryoconcervation as a method of long-term storage in collections of microorganisms.

24-29

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ֲ STAPHYLOCOCCUS AUREUS Ͳ
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THE PERSISTENCE OF STAPHYLOCOCCUS AUREUS AMONG THE STUDENTS OF THE MEDICAL COLLEGE
Zamazy T.M., Malanova O.M., Kuchma M.V.,Rudenko L.M., Bolshakova G.M.
The persistence of Staphylococcus aureus among the students of the medical college was studied.  The general microbiological methods for quantitative and qualitative characteristic of the isolated staphylococcus strains were applied. 26 from 90 conditionally healthy students were the carriages of S.aureus. Almost half from them (12) were ill often with respiratory diseases, at 5 - chronic tonsillitis is diagnosed and only 9 - were healthy carriages. The isolated strains were characterized by many (3-5) factors of pathogenicity, that allowed to regard them as the potential etiological agents of the pyoinflammatory processes of the skin, the opened wounds, the hospital pneumonias and other.

30-33

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BIOCENOSIS OF ORAL CAVITY AS A INDICATOR OF HEALTH FOR CHILDREN OF TINEAGER AGE|
Baydalka I.D
The biocenosis of oral cavity in teenagers including specifics features of somatic and dental pathology was investigated. Difference of the biocenosis types for these groups children was detected and proposed its using as an indicator of health.

34-36

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70-в ² 45-в -òί IJҲ.  в Ͳ
 

39-45

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