Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
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Çì³ñò (Contents) |
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ÎÃËßÄÈ (REVIEWS) |
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| ÏÐÎÒÈÂÎÌÈÊÐÎÁÍÀß ÀÊÒÈÂÍÎÑÒÜ È ÔÀÐÌÀÊÎËÎÃÈ×ÅÑÊÈÅ ÝÔÔÅÊÒܲ ÔÅÍÎËÜÍÜ²Õ ÑÎÅÄÈÍÅÍÈÉ Âîëÿíñêàÿ Í.Ï., Ãðèöåíêî È.Ñ. ANTIMICROBIC ACTIVITY AND PHARMACOLOGICAL EFFECTS OF PHENOLIC SUBSTANCES Volyanskaya N.P., Gritsenko I.S. The review
of a biological potency of antimicrobic action and pharmacological
properties of phenol’s derivatives is resulted. The prospect of search
in series of phenol’s derivatives effec-tiveness and nontoxic
antimicrobic substances is certain.
Keywords: Phenolum, antimicrobic activity, toxicity. |
3-7 |
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| ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ ÏÐÀÖ² |
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| ̲Æ̲ÊÐÎÁͲ ÂÇÀªÌβÄÍÎÑÈÍÈ ÀÍÒÀÃÎͲÑҲ ÒÀ ÑÈÌÁ²ÎÍҲ ÏΠ²ÄÍÎØÅÍÍÞ ÄÎ HELICOBACTER PYLORI Áàáè÷ ª.Ì., Ñêëÿð Í.²., Âîëÿíñüêèé Þ.Ë., Æäàìàðîâà Ë.À., Á³ëîçåðñüêèé Â.². MICROBIAL INTERACTIONS OF ANTAGONISTS AND SYMBIONTS IN RELATION TO HELICOBACTER PYLORI Babych Å.Ì., Sklyar N.I., Volyansky Y.L., Zhdamarova L.À., Belozersky V.². The
results on determination of character of microbial interactions of 158
associations isolated from bioptic samples of gastroduodenal tract in
109 patients with peptic ulcer and gastroduodenites are presented in
this paper. Microorganisms-symbionts and antagonists in relation to
Helicobacter pylori have been determined which were characterized by
both high and low potential of enzyme activity. Within the group of
bacteria which actively inhibited vital functions of helicobacters
there were determined strains which are found to be competitors as well
to the concomitant mucosal microflora with high potential of enzyme
activity and to microorganisms-symbionts for Helicobacter pylori. The
strains isolated are promising for development of probiotic
preparations.
Key words: Helicobacter pylori, mucosal microflora, microbial interactions, gastroduodenal pathology |
4-11 |
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| ÂÏËÈ ÏΪÄÍÀÍÈÕ ÀÁ²ÎÒÈ×ÍÈÕ ÔÀÊÒÎв ÍÀ ÂÅÃÅÒÀÒÈÂͲ ÂËÀÑÒÈÂÎÑÒ² SALMONELLA TYPHIMURIUM Äåðêà÷ Ñ.À., Íîñàòåíêî À.²., Êðèëîâà ².À., Ãàáèøåâà Ë.Ñ., Äàâèäåíêî Ì.Á., Ñòðîãà Î.²., Þäèí ².Ï., ˳òêåâè÷ Ã.Í. EFFECT OF COMBINED ABIOTIC FACTORS ON VEGETATIVE PROPERTIES OF SALMONELLA TYPHIMURIUM Derkach S.A., Nosatenko A.I., Krylova I.A., Gabisheva L.S., Davidenko M.B., Litkevich A.A. The
results of the influence of different abiotic factors on the vitality
of the culture of Salmonella typhimurium were revealed. The role of
medium (tap water, water from melted snow), temperature conditions of
cultivation.
Key words: Salmonella typhimurium, nutrition medium, abiotic factors.
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12-17 |
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| ÂÈÂ×ÅÍÍß ÀÍÒÈÃÅÍÍί ÑÒÐÓÊÒÓÐÈ ØÒÀ̲ ÁÀÊÒÅÐίIJ ÔÐÀÃ²Ë²Ñ Äÿ÷åíêî Â.Ô., Ìàðþùåíêî À.Ì., ßãíþê Þ.À., Áàêóìåíêî À.Â. THE STUDY OF THE ANTIGENICAL STRUCTURE OF BACTEROIDES FRAGILIS Diachenko V.F., Mariushenko A.M., Yahniuk Yu.A., Bacumenko A.V. The common
polysaccharide antigen of Bacteroides fragilis strains was
investigated. The strains used in this study were: B.fragilis (¹
13/83), B.fragilis (¹323) and recent clinical isolates. The
polysaccharide antigen extracted by aqueous phenol methods. A specific
antiserum against Bacteroides fragilis strains polysaccharide antigen
was prepared. The study indicated that in most strains of Bacteroides
fragilis the common polysaccharide antigen was present.
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18-21 |
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| Ê ÂÎÏÐÎÑÓ ÏÎÂÛØÅÍÈß ÝÔÔÅÊÒÈÂÍÎÑÒÈ ÈÑÏÎËÜÇÎÂÀÍÈß ÀÍÒÈÁÀÊÒÅÐÈÀËÜÍÛÕ ÑÐÅÄÑÒ ÏÐÈ ÊÈØÅ×ÍÛÕ ÈÍÔÅÊÖÈßÕ Êîçüêî Â. Í., Àíäðóùåíêî È. Í., Áåëîêîíü È. Ô., Âîëÿíñêèé À. Þ., Êàçìèð÷óê Â. Â., Øóëüãà Í. Í., Ñïèðèäîíîâ À.  , Ïîâîëîêèíà È.Â. TO QUESTION OF INCREASE OF EFFICIENCY OF THE USE OF ANTIBAÑTERIAL FACILITIES AT INTESTINAL INFECTIONS Kozko I. N., Andrushenko I. N., Belokon I. F., Volyanskiy A. Yu., Kazmirchuk V. V., Shulga N. N., Spiridonov A. V, Povolokina I.V. Reduction
of valid for one occasion dose on the reception in 1,5 - 2 times
antibacterial facilities on the example of pills of norfloksacyn in
combination with the «Polidekanit granules» rendered the expressed
therapeutic effect not different from an effect in a control group, but
considerably lowered the risk of display of negative influences of
antibiotic. The offered combination of preparations causes complete
sanation from pathogenic microorganisms, having minimum influence on
the useful flora of intestine. Introduction to combination of
preparation with action enveloping and adsorbent is accompanied by the
considerable increase of specific antibacterial activity due to
deceleration of suction and increase of display of action of antibiotic
on intestinal microflora. Introduction of the given complex method of
the medical treatment sharp intestinal infections in clinical practice
will allow to decrease side effects, duration of course of medical
treatment of patients, and also expenses on the medicinal providing.
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22-26 |
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| ÓÄÎÑÊÎÍÀËÅÍÍß ÌÅÒÎÄÓ ÑÀͲÒÀÐÍÎ-ÁÀÊÒÅвÎËÎò×ÍÎÃÎ ÊÎÍÒÐÎËÞ ÇÀ вÂÍÅÌ ÊÎÍÒÀ̲ÍÀÖ²¯ ËÅòÎÍÅËÀÌÈ ÎÁ’ªÊҲ ÑÅÐÅÄÎÂÈÙÀ ÆÈÒҪIJßËÜÍÎÑÒ² Êðàñîâñüêèé Â.Â., Øàãóí Â.Ã., Òèì÷åíêî Î.Ì., Ïîõèë Ñ.². IMPROVEMENT OF THE METHOD OF SANITARY-BACTERIOLOGICAL CONTROL OF THE LEVEL OF CONTAMINATION OF HABITAT OBJECTS BY LEGIONELLA Krasovsky V.V., Shagun V.G., Timchenko O.M., Pokhil S.I. Effect of
different selective factors (heating, acid action, antibiotics, dyes,
etc.) on Legionella spp. and on microorganisms of other taxonomic
groups has been studied in experiments with model and natural water
samples. It was concluded that during the sanitary-bacteriological
control of water systems of natural and man-caused origin to determine
their contamination level by Legionella spp (CFU/ml) in a more precise
manner it is necessary to use the determined correction factor (1 -
2·104) corresponding to each selective factor.
Key words: Legionella, bacteriological method, determination of concentration, correction factor |
27-34 |
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| ÏÐÎÔÅÑÑÈÎÍÀËÜÍÛÅ ÇÎÎÍÎÇÛ ÕËÀÌÈÄÈÉÍÎÉ ÝÒÈÎËÎÃÈÈ Íåõîðîøèõ Ç.Í., Ìàëèêîâà Ì.Â., Áîùåíêî Þ.À., Áðîøêîâ Ì.Ì., Øåâ÷óê Ë.È., Ìàëüöåâà Ò.Â., Äæóðòóáàåâà Ã.Í. PROFESSIONAL ZOONOSES OF CHLAMYDEOUS ETIOLOGY Nekhoroshikh Z.N., Malikova M.V., Boschenko Yu. A., Broshkov M.M., Shevchuk L.I., Ìàlceva T.V., Djortubaeva G.N. The
results of chlamydeous infection spread study in agriculture animals
and in professional contingents are given. Complex of measures, that is
directed on zoonosis chlamydeousis prophylaxis, is proposed.
Key words: Chlamydiosis, Zoonoses, Ðrofessional contingents, Animals. |
35-41 |
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| ÕÀÐÀÊÒÅÐÈÑÒÈÊÀ
ÄÐÅÉÔ-ÂÀÐÈÀÍÒÎÂ ÂÈÐÓÑÎÂ ÃÐÈÏÏÀ À, ÂÛÄÅËÅÍÍÛÕ Â ÐÀÇÍÛÅ ÃÎÄÛ
ÝÏÈÄÅÌÈ×ÅÑÊÈÕ ÏÎÄÚÅÌΠÇÀÁÎËÅÂÀÅÌÎÑÒÈ ÃÐÈÏÏÎÌ Â Ã. ÕÀÐÜÊÎÂÅ Ïàí÷åíêî Ë.À., Âîëÿíñêèé Þ.Ë., Êðàòåíêî È.Ñ., Ãåðàñþòà Í.Í., Îäðàæèé Í.Ê., Òîðÿíèê È.È., Êîðîâàåâà È.Â., Èëüèíà È.Ï. CHARACTERISTIC OF THE DRIFT-VARIANTS OF INFLUENZA A VIRUSES, ISO-LATED IN DIFFERENT EPIDEMIC YEARS IN KHARKOV Panchenko L., Volyansky U., Kratenko I., Gerasujta N., Odraziy N., Toranik I., Korovaeva I., Ilina N. The
drift-variants of influenza a viruses with different antigenic
properties were isolated in the epidemic years in Kharkov. In 1986
influenza À(H3N2) virus was dominanted, which was isolated on the
gallinaceae embryos. In 2003 - À(H1N1) virus, which was isolated on the
cells culture MDSK.
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42-48 |
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| ÑÎÑÒÎßÍÈÅ ÀÍÒÈÌÈÊÐÎÁÍÎÃÎ ÈÌÌÓÍÈÒÅÒÀ Ó ÁÎËÜÍÛÕ ÊÎÌÁÈÍÈÐÎÂÀÍÍÛÌÈ ÔÎÐÌÀÌÈ ÝÍÄÎÌÅÒÐÈÎÇÀ Ïîïîâ Í.Í., Îâ÷àðåíêî À.Ñ., Ðîìàíîâà Å.À., Âîëêîâ Ò.À. THE STATE OF ANTIMICROBIC IMMUNITY OF PATIENTS WITH COMBINED FORMS OF ENDOMETRIOSIS Popov N.N., Ovcharenko A.S., Romanova E.A., Volkov T.A. The
examination of 86 patients testify that endometriosis is taking at the
background of disturbed microbiocenosis of the genitals and fall of
antimicrobic immunity. The patients demonstrate low antimicrobic
antibodys titres, its affinity and degree of glycosilation in
comparison with healthy womans.
Key words: endometriosis, antimicrobic immunity |
49-52 |
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| ÎÏÒÈ̲ÇÀÖ²ß ÃÅÌÎÏÎÅÇÓ ÀÍÒÅÍÀÒÀËÜÍÎ ÎÏÐÎ̲ÍÅÍÎÃÎ ÏÎÒÎÌÑÒÂÀ ÙÓв ²Ç ÇÀÑÒÎÑÓÂÀÍÍßÌ Ê˲ÒÈÍÍί ÒÐÀÍÑÏËÀÍÒÀÖ²¯ Ðîìàíîâà Î.À., Ñèäîðåíêî Ò.À., ²ãóìíîâà Í.²., Þõèìåíêî Â.². OPTIMIZATION OF HEMOPOIESIS OF ANTENATALY IRRADIATION POSTERITY OF RATS BY APPLICATION OF CELLULAR TRANSPLANTATION Romanova E.A., Sidorenko T.A., Igymnova N.I., Yuchimenko V.I. The aim of
study is influence of allogenic cellular myelotransplant in the
subtransplantation doses (1,5x104 and 3,0x104 cells) to the hemopoiesis
of rats, which were irradiated in the early embryonic period. It was
found out that less dose of mielocaryocytes was more effective for
normalization of hemopoietic variational parametess. It was shown that
cellular bone marrow transplant may be apple with aim of regulation of
pathologic hemopoiesis.
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53-58 |
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| ÄÎ ÏÐÎÁËÅÌÈ ÑÀËÜÌÎÍÅËÜÎÇÍί ²ÍÔÅÊÖ²¯ Ñëàäêîâà Ë.Ì., Ðèæåíêî Ñ.À., Ñòåöåíêî ².Þ., Ñåìåíÿê Ì.Â. ABOUT PROBLEM OF SALMONELLOSIS INFECTION Sladkova L.M., Rizenko S.A., Stetsenko I.Yu., Semenyuk M.V. Deep
retrospective epidemiologic analysis and studing of heteroantigens is
caused by high level of salmonellosis. It has been determined the great
meaning of infections pathology of macroantigens and microorganismus.
During salmonellosis epidemiological process great attention is paid to
antigenic infections excitement. It has been determined deep connection
of correspondence with specific buteroantigen of bacterium polymorphism
according to blood group of patients with salmonellosis.
Key words: salmonellosis, epidemic process, iso- enteroantigens, epidemic analysis, strains, diagnostics, statistics. |
59-63 |
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| ÌÎÄÈÔ²ÊÀÖ²ß ÑÒÐÓÊÒÓÐÈ Ã²ÄÐÎÊÑÈÀÏÀÒÈÒÓ ÉÎÍÀÌÈ ÌÅÒÀ˲Â- ÊÎÌÏÎÍÅÍÒÀÌÈ ÌÅÄÈ×ÍÈÕ ²ÌÏËÀÍҲ Ñóõîäóá Ë.Ô., Êó÷ìà ².Þ., Ñóõîäóá Ë.Á., Âîëÿíñüêèé À.Þ. MODIFICATION THE STRUCTURE OF HYDROXYAPATITE BY METAL IONS- COMPONENTS OF MEDICAL IMPLANTS Sukhodub L.F., Kuchma I.Yu., Sukhodub L.B., Volyansky A.Yu. In the
paper one of the problems connected with an interface “ implant-bones”,
namely, the influence of metal ions-constituents of medical implants on
the hydroxyapatite structure is described.
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64-69 |
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| ÅϲÄÅ̲×ÍÀ ÑÈÒÓÀÖ²ß Ç ÒÓÁÅÐÊÓËÜÎÇÓ Ó ËܲÂÑÜÊ²É ÎÁËÀÑÒ² Òàðàñþê Î.Î., Áîðèñ Â.Ì., Êîñòèê Î.Ï., Âåðá³íåöü À.Â., Çàð³÷íà Î.Ç., Ãîëóá÷åíêî Ë.Ê., Êîãóò Î.Ì., Ïóðñüêà Ì.Á., ³â÷àð ².Ñ., Çàâ`ÿëê³í Â.Ì., Ìóäðèê Ã.À. EPIDEMIC SITUATION WITH TUBERCULOSIS IN THE LVIV REGION Tarasyuk O.O., Borys V.M., Kostyk O.P., Verbinets A.V., Zarichna O.Z., Golubchenko L.K., Kogut O.M., Purska M.B., Vivchar I.S., Zavyalkin V.M., Mudryk G.A. The
epidemic situation with tuberculosis in 20 districts of the Lviv region
for 2000-2004 years are investigated and analysed. The basic tendencies
with tuberculosis in different age groups are determined. The changes
in frame of the forms of a tuberculosis, feature of a pathomorphism of
a tuberculosis in modern conditions are investigated. The situation
with tuberculosis for last 5 years in the Lviv region remains stable,
except for a situation in mountain and foothill districts. The
stability of the revealed tendencies permits to hope on improvement of
epidemic situation as a whole.
Key words: epidemiology of a tuberculosis |
71-76 |
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| ÌÅÒÎÄ ÊÎÐÅÊÖ²¯ ÄÈÑÁ²ÎÇÓ ÒÎÂÑÒÎÃÎ ÊÈØÅ×ÍÈÊÓ Òàðàñþê Î.Î., Øèøêà Ã.Â., Ìàëàõîâ Â.Ê., Ëîìíèöüêà Â.Á.,.Ïðóíüêî Ò.Ä., Äóáèöüêèé ².Ì., Ñèäîð Ë.Ì., Øïàòàðþê Î.Â., Ìîòà Á.ª. METHOD OF CORRECTION OF DISBIOSES OF A LARGE INTESTINE Òàrasyuk O.O., Shyshka H.V., Ìàlahov V.Ê., Lomnytska V.B., Prunko Ò.D., Dubytskyi I.N., Sydor L.N., Shpataryuk Î.V., Ìîtà B.Å. In
conditions of a chronic intoxication with a mixture of heavy metals
with compounds of suphur the expressed dysbacteriosis of a large
intestine develops. In experiment the expediency of applying of binary
medical complexes “ spirulina + lactobacterinum ”, “ spirulina +
bacteriophage ” and three-component medical complex “ spirulina +
bacteriophage + lactobacterinum” for êîðåêöèè of microecological
changes in a large intestine is demonstrated.
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77-81 |
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| ÏÎвÂÍßËÜÍÀ ÕÀÐÀÊÒÅÐÈÑÒÈÊÀ ÌÅÒÎIJ ÐÓÉÍÓÂÀÍÍß Ê˲ÒÈÍ Ì²ÊÐÎÎÐÃÀͲÇ̲ ÄËß ÎÒÐÈÌÀÍÍß ²ÍÒÀÊÒÍÈÕ ÔÎÐÌ ÏËÀÇ̲ÄÍί ÒÀ ÕÐÎÌÎÑÎÌÍί ÄÍÊ Òèì÷åíêî Î.Ì., Ïîõèë Ñ.². COMPARATIVE CHARACTERISTIC OF METHODS FOR DESTRUCTION OF MICROORGANISMS CELLS TO OBTAIN INTACT FORMS OF PLASMID AND CHROMOSOMAL DNA Timchenko O.M., Pokhil S.I. To
destruct cells of bacteria from different taxonomic groups with purpose
to isolate chromosomal and plasmid DNA (ChrDNA, PlDNA) there were
tested experimentally seven the most widespread methods: ultrasonic
(gaseous cavitation) disintegration method (USM), guanidinium
thiocynate method (GTM), proteinase K – method (PKM), method of rapid
mini-lysis (MRML), method of alkaline lysis (MAL), method of triton
lysis (MTL), method of lysis in agarose blocks (MLAB). MRML, MTL and
MLAB are the most efficacious (by percent of destructed bacterium
cells, free DNA concentration, integrity level for molecules ChrDNA,
PlDNA) for genotyping of microorganisms strains.
Key words: efficacy of methods, cells destruction, isolation of DNA |
82-90 |
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| ÈÑÒÎÐÈÊÎ-ÔÈËÎÑÎÔÑÊÈÅ ÀÑÏÅÊÒÛ Ó×ÅÍÈß Î ÏÐÈÐÎÄÅ ÈÍÔÅÊÖÈÎÍÍÛÕ ÁÎËÅÇÍÅÉ Â ÒÐÓÄÀÕ È.È. ÌÅ×ÍÈÊÎÂÀ Ïóãà÷ Í.Á. THE HISTORICAL AND PHILOSOPHICAL ASPECTS OF MECHNIKOV`S THEORY ABOUT ORIGINS OF INFECTIONS DISEASES Pugach N. Â. In the
work the author pays attention to the theoretical and cognitive
aspects. I.I. Mechnikov’s scientific work which are not enough
explored. It is made logical reconstruction of genesis and development
of phagocyte theory, its creative methods. The author investigates some
questions of heuristic function of phagocyte cellura theory of
immunity. Here it is also determined the role of experiment in the
explanation of complicated correlations of pathogenic microbe and human
and animal organism.
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91-97 |
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