Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-5 |
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ÎÃËßÄÈ (REVIEWS) |
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ÂÀÍÊÎÌÈÖÈÍÐÅÇÈÑÒÅÍÒÍÛÅ ÝÍÒÅÐÎÊÎÊÊÈ (ÎÁÇÎÐ ËÈÒÅÐÀÒÓÐÛ) Ìèðîíåíêî Ë.Ã., Ïåðåòÿòêî Å.Ã. VANCOMYCIN RESISTANT ENTEROCOCCUS (THE REVIEW OF PAPERS) Myronenko L. G., Peretyatko E. G. Papers
data about the role of Vancomycin-resistant enterococcus in appearing
of nosocomial infection are generalized. The mechanisms of resistance
formation to glycopeptidal antibiotics are described. The necessity of
microbiological monitoring of vancomycin resistance of enterococcus
conducting is grounded.
Key words: enterococcus, vancomycin resistance, microbiological monitoring. |
6-10 |
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| ÏÀÒÎÃÅÍÍÈÉ
ÏÎÒÅÍÖ²ÀË RAHNELLA AQUATILIS: ÄÎÑ˲ÄÆÅÍÍß ÔÀÊÒÎв ÏÀÒÎÃÅÍÍÎÑÒ², ßʲ
²ÄÏβÄÀÞÒÜ ÇÀ ÇÄÀÒͲÑÒÜ ÐÀÕÍÅË ÊÎËÎͲÇÓÂÀÒÈ ÒÐÎÏͲ ÒÊÀÍÈÍÈ ÎÐÃÀͲÇÌÓ
ÃÎÑÏÎÄÀÐß Ïîõèë Ñ.². PATHOGENIC POTENTIAL OF RAHNELLA AQUATILIS: THE STUDY OF PATHOGENS FACTORSBEING RESPONSIBLE FOR RAHNELLA ABILITY TO COLONIZE SUSCEPTIBLE TISSUES OF HOST ORGANISM Pokhil S.I. In 24
strains of R. aquatilis, there were revealed pathogens factors which
provide these microorganisms with potential to colonize susceptible
tissues of host organism: high adhesive activity; ability to produce
extracellular metabolites having bacteriocinic and repellent activity
to representatives of indigenic microflora of human intestine;
antilysozyme activity. R. aquatilis strains showed low level of
proteinase and neuroaminidase activity and did not produce lecithinase.
Termoregulation effects on intensity action of R. aquatilis pathogens
factors.
Key words: Rahnella aquatilis, pathogens factors, colonization of susceptible tissues. |
11-18 |
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| ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ
ÐÎÁÎÒÈ (EXPERIMENTAL STUDY) |
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| ²ÄÅÍÒÈÔ²ÊÀÖ²ß ØÒÀ̲ YERSINIA SPP. ÒÀ ÂÈÇÍÀ×ÅÍÍß ¯Õ ÀÍÒÈÁ²ÎÒÈÊÎÐÅÇÈÑÒÅÍÒÍÎÑÒ² Â’ÿëèõ Æ.Å., Ñóòóëîâà À.À., Êèëèïêî Ë.Â. IDENTIFICATION STRAINS OF YERSINIA SPP. AND TESTING OF RESISTANCE Vyalykh Zh.E., Sutulova A.A.,. KilipkoL.V. The
species identification of freshly isolated strains was performed with
the help of biochemical testing (the total number of strains was 68)
also the sensitivity of this strains to antibiotics was researched.
95,2% of strains which were researched were resistant to ampicilline,
75,8 % – to chloramphenicol, 59,7 % – to tetracycline, 98,4 – 100,0% of
them were sensitive to ciprofloxacine, cephalosporins, aminoglicozids,
imipenem.
Key words: Yersinia, biochemical propertie, resistance.
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19-21 |
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| ÈÇÓ×ÅÍÈÅ ÎÑÎÁÅÍÍÎÑÒÅÉ ÌÈÊÐÎÔËÎÐÛ ÐÀÍÅÂÎÃÎ ÎÒÄÅËßÅÌÎÃÎ ÏÐÈ ËÀÏÀÐÎÑÊÎÏÈ×ÅÑÊÈÕ È ËÀÏÀÐÎÒÎÌÍÛÕ ÂÌÅØÀÒÅËÜÑÒÂÀÕ ÍÀ ÆÅË×ÍÛÕ ÏÓÒßÕ ßãíþê Þ.À., Ìàðþùåíêî À.Ì., Áàêóìåíêî À.Â., Âîëêîâ À.À., Ïÿòàêîâ À.Â. STUDY OF THE MICROBIAL COMPOSITIONS SPECIALITIES OF THE WOUNDED EXUDATE AFTER OF LAPAROSCOPIC AND LAPAROTOMIC OPERATIONS IN BILIARIC TRACTS Yagniuk Yu.A., Mariushchenko A.V., Bacumenko A.V., Volkov A.A., Piatacov A.V. Microbial
compositions of the wounded exudate, which from patients, was studied,
after laparoscopy and laparotomy surgical interferences in biliaric
tracts. It was discowered, that, in comparison with laparotomic
operations, after laparoscopic cholecystectomy in the wounded exudate
during the first day after operacions the maintenance of E.coli and
asporogenic anaerobic bacteries, represented Bacteroides spp., was
increased.
Key words: laparoscopic and laparotomic cholecystectomy, postoperative period, bacterial compositions |
22-24 |
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| ÈÇÓ×ÅÍÈÅ ÃÅÍÅÒÈ×ÅÑÊÎÃÎ ÏÎËÈÌÎÐÔÈÇÌÀ ÌÓÇÅÉÍÛÕ ÊÓËÜÒÓÐ C. DIPHTHERIAE  ÏÎËÈÌÅÐÀÇÍÎÉ ÖÅÏÍÎÉ ÐÅÀÊÖÈÈ Ñ ÓÍÈÂÅÐÑÀËÜÍÛÌÈ ÏÐÀÉÌÅÐÀÌÈ Ìèðîíåíêî Ë.Ã. , Ñàâ÷óê À.È. DISCOVERY OF GENETIC POLYMORPHISM OF C. DIPHTHERIAE MUSEUM CULTURES IN POLYMERASE CHAIN REACTION WITH ARBITRARY PRIMERS Myronenko L.G., Sauchuk A.I. The 12 C.
diphtheriae museum cultures were investigated by polymerase chain
reaction with arbitrary primer ¹ 45. These cultures were isolated in
1954-1959 in Moscow and in 1991 in Kharkov from the patients with
diphtheria and the bacilli carriers. The most typical amplicon profiles
the museum cultures were determined. The level of genetic similarity of
the museum cultures, which manifests by coincidence of the amplicon
profiles, was determined too. This information will allow supplement
the certificates of the museum cultures and creation of the data bank,
which contains information about of the pathogene genomes circulating
in various regions and different epidemic process intensity.
Key words: C. diphtheriae, polymerase chain reaction with arbitrary primers, certificate of bacterial culture. |
25-28 |
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| ÑÊÐÈͲÍà ÏÐÅÏÀÐÀÒ²Â-ÊÀÍÄÈÄÀҲ  ÀÄ′ ÞÂÀÍÒÈ Ì²ÊÐÎÁÍÎÃÎ ÏÎÕÎÄÆÅÍÍß ÇÀ ¯Õ ÂÏËÈÂÎÌ ÍÀ ÔÀÃÎÖÈÒÀÐÍÓ ÀÊÒÈÂͲÑÒÜ IN VITRO ªëèñåºâà ².Â., Áàáè÷ ª.Ì., Ñêëÿð Í.²., Âîëÿíñüêèé Þ.Ë., Á³ëîçåðñüêèé Â.²., Æäàìàðîâà Ë.À., ̳øóêîâà Ñ.À., Ñèäîðåíêî Ò.À., ²ãóìíîâà Í.²., ªâñþêîâà Â.Þ., Ðèæêîâà Ò.À. SCREENING OF MICROBIAL ORIGIN PREPARATIONS WITH POTENTIAL ADJUVANT PROPERTIES ACCORDING TO THEIR INFLUENCE UPON PHAGOCYTIC ACTIVITY IN VITRO Yelyseyeva I.V., Babych Ye.M., Sklyar N.I., Volyansky Yu.L., Belozersky V.I., Zhdamarova L.A., Myshukova S.A., Sydorenko T.A., Igumnova N.I., N.I.Yevsyukova V.Yu., Ryzhkova T.A. Undertaken
study is devoted to search of effective microbial origin adjuvants for
development immunogenic oral vaccines against diphtheria. It’s
investigated influence of filtrates of microbial cultures prepared from
strains of Corynebacterium and Lactobacillus spp. upon phagocytic
activity of human’s and animal neutrophilic leukocytes in vitro.
Filtrates prepared from C. pseudodiphtheriticum and L. plantarum
appeared as the most perspective ones according to investigated indices
of phagocytosis.
Key worlds: adjuvants, phagocytosis, vaccines against diphtheria, Corynebacterium, Lactobacillus. |
29-33 |
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| ÑÓÏÅÐÎÊÑÈÄÄÈÑÌÓÒÀÇÍÀ
ÀÊÒÈÂͲÑÒÜ ÒÀ Â̲ÑÒ ÔÅÐÌÅÍÒÀÒÈÂÍÎ- ÀÊÒÈÂÍÎÃÎ ÖÅÐÓËÎÏËÀÇ̲ÍÓ ÑÈÐÎÂÀÒÊÈ
ÊÐβ ÙÓв вÇÍÎÃΠ²ÊÓ ÇÀ ÓÌΠ²ÌÓͲÇÀÖ²¯ ÀÄÏ-ÀÍÀÒÎÊÑÈÍÎÌ Âîëÿíñüêèé À.Þ., Íèêèò÷åíêî Þ.Â., Ñèìèðåíêî Ë.Ë., Êó÷ìà ².Þ. SUPEROXIDE DISMUTASE ACTIVITY AND ENZYMATICALLY ACTIVE CERULOPLASMIN CONTENT IN BLOOD SERUM OF DIFFERENT AGE RATS IN CONDITIONS OF ADT– ANATOXIN IMMUNIZATION Volyanskiy A.Y., Nikitchenko Yu.V., Simirenko L.L., Kuchma I.Y. Superoxide
dismutase activity and enzymatically active ceruloplasmin content in
blood serum of 1-, 3-, 12-, 24- and 32–month old control male Wistar
rats, and dynamics of change of these parameters in 3 – and 20 – month
old rats during the forming of antitoxic immunity to diphtheria and
tetanus anatoxins under immunization by ADT – vaccine were
investigated. The activity of enzymes utilizing superoxide radicals
characterizes by age peculiarities both before immunization and in
dynamics of immune response to vaccination. Key words: superoxide
dismutase, ceruloplasmin, ADT – anatoxin, rats, age.
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34-37 |
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