Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-4 |
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ÎÃËßÄÈ (REVIEWS) |
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| ÅÐ˲ղÎÇ – ÍÎÂÀ ÏÐÎÁËÅÌÀ ÄËß ÌÅÄÈÖÈÍÈ Êèëèïêî Ë.Â., Òèì÷åíêî Î.Ì., Ïîõèë Ñ.²., Þðêî Ê. EHRLICHIOSIS IS A NEW PROBLEM FOR MEDICINE Kilipko L.V., Timchenko O.M., Pokhil S.I., Yurko K.V. Ehrlichia infection, ehrlichiosis, is a group of transmissive human and mammal diseases caused by intracellular pathogens, bacteria of genera Ehrlichia. There have been analyzed scientific achievements and considered generalizations concerned classification and biological properties of bacteria of genera Ehrlichia (including sensitivity to antibiotics and pathogen potential), pathogenesis, epidemiology, clinical presentation, up-todate methods of laboratory diagnostics, treatment and prophylaxis of ehrlichiosis. Key words: ehrlichiosis, properties of causative agent, pathogenesis, epidemiology, clinics, diagnostics, treatment, prophylaxis. |
5-13 |
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| ÂÈÊÎÐÈÑÒÀÍÍß ÏÎ˲ÌÅÐÀÇÍί ËÀÍÖÞÃÎÂί ÐÅÀÊÖ²¯  IJÀÃÍÎÑÒÈÖ² ²ªÐÑÈͲÎÇÍί ²ÍÔÅÊÖ²¯ Ïîë³ùóê Í. Ì., ̳ç³í Â.Â., Íîâ³êîâ Ñ.Â., Øàò³ëî Þ.Â., Êó÷ìà ².Þ. THE APPLICATION OF POLYMERASE CHAIN REACTION IN YERSINIA INFECTIONS DIAGNOSTICS Polishchuk N.N., Misin V.V., Novikov S.V., Shatilo Y.V., Kuchma I.Y. The modern
sight at the possibilities of polymerase chain reaction application in
Yesinia infections diagnostics is presented in the work. The data about
high effectiveness of PCR, as compared with conventional methods of
research, in revealing of intestinal yersiniosis and pseudotuberculosis
are represented. The results of genetic structure analysis of
Y.pseudotuberculosis and Y.enterocolitica, that are necessary for
working out the epidemiological markers for Yesinia distribution
surveillance are described. The data from references testify to
necessity of development of new and improvement of existing
genemolecular research methods for Yesinia infections diagnostics.
Key words: Y.pseudotuberculosis, Y.enterocolitica, PCRresearches, a genotype, genotyping, epidemiological surveillance |
14-18 |
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| ̲ÊÐÎÔËÎÐÀ ÃͲÉÍÈÕ ÐÀÍ ÒÀ ÑÓ×ÀÑͲ ϲÄÑÒÓÏÈ ÙÎÄÎ ÇÀÑÒÎÑÓÂÀÍÍß ÀÍÒÈÑÅÏÒÈʲ  ղÐÓÐò×Í²É ÏÐÀÊÒÈÖ². ÎÃËßÄ Ë²ÒÅÐÀÒÓÐÈ Âîëêîâ À.Î., Áîëüøàêîâà Ã.Ì. THE VAGINAL MIKROFLORA OF REPRODACTIVE AGE`S WOMEN IN THE NORM AND AT DIFFERENT PATOLOGIC PROCESSES. REVIEW. Volkov A.O., Bolshakova G.M. The data
of scientific literature, concerning the microflora of wounds of
various origin are presented. Modern approaches of the treatment with
use of various physical and chemical methods of influence on the
microorganisms and their sensitivity to antibiotics are considered.
Key words: microflora of wounds, treatment, antibiotics, antiseptics.
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19-23 |
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ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ ÐÎÁÎÒÈ (EXPERIMENTAL STUDY) |
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| IMMUNOLOGICAL FEATURES OF THE MODEL OF RADIATION- INDUCED ANTI- INFECTIOUS RESISTANCE DEFECT Kolyada T.I., Brusnik S.V., Sklyar N.I., Michailichenko M.S., Nesterenko A.M., Kolyada O.N. In course of the present work a model of radiationinduced anti-infectious resistance defect was developed. The research has shown that infection with Salmonella typhimurium of the postnatally irradiated Wistar rats in the dose range of 0,75 - 1,5 Gy leads to the complex defect of anti- infectious resistance, characterized with the following features of immune system activation: phagocytosis depression, the increase in proinflammatory cytokines levels -TNF-α level was (94,07±2,67) pg/ml, the decrease in the general complement level (36,75±1,75) h.u. and an increase in circulating immune complexes (0,009±0,0007) o.d.u. The developed model can be used in order to evaluate the consequences of irradiation at any time after exposition and methods of their correction.
Key words: low-dose irradiation, anti-infectious resistance, Salmonella typhimurium, immunological parameters. |
24-28 |
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| CLINICO-MORPHOLOGICAL ANALYSIS OF THE MATERIALS FROM ENT-PATIENTS WITH MIXED VIRAL-BACTERIAL INFECTION Torianyk I.I., Panchenko L.A., Popova N.G., Korovaeva I.V. The article
contains the materials on clinicomorphological diagnosis in ENT-
patients with mixed viral and bacterial infection. It is specified that
the conditions of mixed infection development increase the
etiopathogenic effects which makes the disease clinical presentation
significantly more severe, its manifestations polymorphous and prolongs
its clinical course. The somatic signs typical for infection diseases
are supplemented by mental disorders, which show the inversion of
personal and volitional properties. The formation of the symptom
complex effects the organism in a whole against a background of
structural and functional changes of its organs (pharynx, larynx,
bronchi) which can have both specific and unspecific character. It is
interesting that dominating are the signs of morphologic changes, which
have been traditionally treated as virogenic (nucleus- to- cytoplasm
ratio, nonstable sorption ability of cytoplasm, sorption and cumulation
ability of nuclei).
Key words: ENT- patients, clinico-morphological analysis, mixed viral and bacterial infection, pharynx, larynx, bron |
29-31 |
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| EFFECTS OF ELECTRON BEAM AND OZONE COMBINED PROCESSING ON VARIABILITY OF THE RESIDUAL MICROFLORA Babych E.M., Sklyar N.I., Ryzhkova T.A., Kalinichenko S.V., Semerenskaya E.I. The
article is devoted to study of possible phenotypic changes in
individual representatives of the sanitarymodel microflora in natural
water and sewages induced by the electron beam and ozone combined
processing. The results obtained at the given stage permit us to state
that the presented technique of the water disinfection does not injure
microecology of the environment.
Key words: variability of microorganisms, disinfection of water, ozone, electron beam, sanitary-indicative microorganisms |
32-36 |
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| ÂÏËÈ ÅÍÕÀÍÑÅв ÍÀ ØÂÈÄʲÑÒÜ ÍÀ ØÂÈÄʲÑÒÜ ÏÐÎßÂÓ ÊÎËÎÍ²É ÁÀÊÒÅÐ²É ÒÀ ÃÐÈÁ²Â ÍÀ ÙÈËÜÍÈÕ ÆÈÂÈËÜÍÈÕ ÑÅÐÅÄÎÂÈÙÀÕ Îñîëîä÷åíêî Ò.Ï., Áàòðàê Î.À., ̳ç³í Â.Â., Ñ.Ã., ×óïðèíîâà Ñ.²., Ðÿäîâà ².Ñ., Øòèêåð Ë.Ã. THE INFLUECE OF ENHANCERS ON APPEARING RATE OF BACTERIALS AND FUNGOUS COLONIES Osolodchenko T.P., Batrak E. A., Mizin V.V., Malanchuk S.G., Chuprinova S.I., Zavada N. P., Rjabova I.S., Shtiker L.G. Influence
of growth factors of microorganisms (enhancers) on occurrence of the
first colonies and on increase in a biomass of microbic cells and
fungous is studied. It is investigated,that increase qualities of
microorganisms considerably increase on nutrient mediums with addition
enhancers in comparison with standards medium. Concentration enhancers
slightly Influences speed of increase in a form make colony of
microorganisms and mushrooms for the certain interval of time.
Key words: microorganisms, fungous, medium, enhancers |
37-40 |
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| ÑÎÇÄÀÍÈÅ ÀÏÀÒÈÒ-ÀÍÒÈÁÀÊÒÅÐÈÀËÜÍÎÃÎ ÊÎÌÏÎÇÈÒÍÎÃÎ ÏÎÊÐÛÒÈß ÍÀ ÒÈÒÀÍÎÂÎÌ ÑÓÁÑÒÐÀÒÅ Ñ ÈÑÏÎËÜÇÎÂÀÍÈÅÌ ÒÅÐÌÎÄÅÏÎÇÈÒÍÎÉ ÒÅÕÍÎËÎÃÈÈ Ñóõîäóá Ë.Á., Âîëÿíñêèé À.Þ., Îñîëîä÷åíêî Ò.Ï., Êó÷ìà È.Þ., Âîëêîâ À.À., Ìèçèí Â.Â. CREATION APATITE-ANTIBACTERIAL OF A COMPOSITE COVERING ON TITANIC SUBSTRATE WITH USE OF THERMODEPOSITARY TECHNOLOGY Sukhodub L.B., Volyanskiy A.Yu., Osolodchenko T.P., Kuchma I.Yu., Volkov A.A., Mizin V.V. Apatite-antimicrobial
composite coverings on the titanic substrate obtaind by
thermodepositary technology have been studied. Antimicrobic activity of
4 titanic plates against referential strains of Staphylococcus,
Escherichia, Pseudomonas and Candida has been studied. It has been
proved, that aethonium and decamethoxinum in enough quantity is sorbed
on a surface of a titanic composite that attacas to structure prolonged
antimicrobic activity.
Key words: apatite, the titan, aethonium, decamethoxinum, referential microbes, activity. |
41-49 |
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| ÀÍÒÈÁ²ÎÒÈÊÎÐÅÇÈÑÒÅÍÒͲÑÒÜ ÇÁÓÄÍÈʲ ÃͲÉÍÎ-ÇÀÏÀËÜÍÈÕ ÓÑÊËÀÄÍÅÍÜ Â ÀÁÄÎ̲ÍÀËÜÍ²É Õ²ÐÓÐò¯ Äÿ÷åíêî Â.Ô., ßãíþê Þ.À., Ìàðþùåíêî À.Ì., ²ñàºâà Ñ.ß., Âîëêîâ À.Î., Áàêóìåíêî À.Â., ßãíþê À.²., Ïÿòàêîâ À.Â. ANTIBIOTICRESISTANCE OF THE PURULOINFLAMMATORY COMPLICATIONS` AGENTS IN THE ABDOMINAL SURGERY Diachenco V.F. Mariushchenko A.M., Yagniuk Yu.A., Isaeva S.J. Volkov A.A., Bacumenko A.V., Yagniuk A.I., Piatacov A.V. Species
spectrum of the puruloinflammatory complications` agents was founded by
bacteriological research, resistance level of the identifid aerobic and
anaerobic agents species to the basic groups of modern antibacterial
preparations was studied.
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50-52 |
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| ÃÅÒÅÐÎÃÅÍͲÑÒÜ
ÇÀ ÊÐÈÒÅвßÌÈ ÊÓËÜÒÓÐÀËÜÍÈÕ ÂËÀÑÒÈÂÎÑÒÅÉ ÒÀ Á²Îղ̲×Íί ÀÊÒÈÂÍÎÑÒ²
̲ÊÐÎÁ²Â ÐÎÄÓ STAPHYLOCOCCUS, ÂÈËÓ×ÅÍÈÕ Â²Ä ÕÂÎÐÈÕ ÍÀ ÏÍÅÂÌÎͲ¯ IJÒÅÉ Â
ÏÅвÎÄ Ç 2003 ïî 2008 ð ð. Øàò³ëî Þ.Â. HETEROGENEITY BY CRITERIA OF CULTURAL PROPERTIES AND BIOCHEMICAL ACTIVITY OF MICROBES OF GENUS STAPHYLOCOCCUS RECEIVED FROM SICK BY PNEUMONIA CHILDREN A DURING THE PERIOD WITH 2003 FOR 2008 Shatilo Y.V. The
characteristic of biological properties of bacteria of genus
Staphylococcus picked out from sick by pneumonia children is resulted.
Heterogeneity of isolates of a staphilococcus by criteria of cultural
properties and biochemical activity is noted.
Key words: Staphylococcus, cultural properties, biochemical activity, pneumonia |
53-57 |
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| ÀÍÒÈÃÅÍͲ ÒÀ ÀÄ'ÞÂÀÍÒͲ ÂËÀÑÒÈÂÎÑÒ² ÅÊÑÏÅÐÈÌÅÍÒÀËÜÍÈÕ ÇÐÀÇʲ ÏÐÅÏÀÐÀҲ ÑÓÁÊ˲ÒÈÍÍÈÕ ÊÎÌÏËÅÊѲ ÇÁÓÄÍÈÊÀ ÄÈÔÒÅв¯ ÏÐÈ ÙÅÏËÅÍͲ ËÀÁÎÐÀÒÎÐÍÈÕ ÒÂÀÐÈÍ ªëèñåºâà ².Â., Áàáè÷ ª.Ì., Æäàìàðîâà Ë.À., Á³ëîçåðñüêèé Â.²., Ñêëÿð Í.²., Êîëïàê Ñ.À., Áîáèðºâà ².Â. ANTIGENIC AND ADJUVANT PROPERTIES OF EXPERIMENTAL SAMPLES OF PREPARATIONS OF SUBCELLULAR COMPLEXES OF THE ACTIVATOR OF THE DIPHTHERIA AT IMMUNIZATION OF LABORATORY ANIMALS Yelyseyeva I.V., Babych Ye.M., Zhdamarova L.A., Belozersky V.I., Sklyar N.I., Kolpak S.A., Bobireva I.V. The
carried out researches are devoted working out of approaches to
improvement of vaccinal preparations against a diphtheria by reception
of antigene microbic fractions of the activator which would raise
antibacterial immunity as the factor of localisation of a diphtheritic
infection in an organism and would stimulate development of antitoxic
immunity. Were studied antigene and adjuvant properties of experimental
samples of antigenic preparations of the activator of a diphtheria. The
received antigene fractions of subcellular complexes of a diphtheria
are capable to stimulate antitoxic humoral immunity at introduction
together with cleared concentrated diphtheritic toxoid and
independently using parenteral and oral immunization schemes.
Key words: antigenic and adjuvant properties, preparations, diphtheria, immunization |
58-65 |
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| ÃËÞÊÎÊÎÐÒÈÊίÄÍÀ ËÀÍÊÀ ÐÅÃÓËßÖ²¯ ÀÍÒÈÒ²ËÎÃÅÍÅÇÓ ÇÀ ÓÌΠòÏÎÒÈÐÅίÄÍÎÃÎ ÑÒÀÍÓ ÎÐÃÀͲÇÌÓ Â ÅÊÑÏÅÐÈÌÅÍÒ² Êó÷ìà ².Þ. GLUCOCORTICOID PART OF ANTIBODY GENESIS REGULATION AT THE HYPOTHYROID STATE OF THE ORGANISM IN EXPERIMENT Kuchma I.J. A
glucocorticoid part of antibody genesis regulation in dynamics of
formation of the humoral immune answer to diphtheritic and tetanic
anatoxins of ADS-vaccine at euthyroid and hypothyroid 3-month's Wistar
males rats was investigated. Changes of corticosteron serum
concentration in the course of the immune answer formation at the
background of an organism hypothyroid state, induced by 1-1-
2-mercaptoimidazol introduction, was described by empirical function of
regression. Serum level of glucocorticoid hormones before vaccination
and in an inductive phase of humoral immune answer formation were bound
to specific antibody genesis activity, that are illustrated by charts
of dispersion and mathematically described by models of correlation and
empirical functions of regression.
Keywords: an organism hypothyroid state, antibody genesis, corticosteron, ADT-anatoxin, rats. |
66-72 |
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