Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-4 |
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ÎÃËßÄÈ (REVIEWS) |
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| ÂÈÐÓÑÛ È ÀÓÒÎÈÌÌÓÍÍÛÅ ÐÅÂÌÀÒÈ×ÅÑÊÈÅ ÇÀÁÎËÅÂÀÍÈß ÂÇÃËßÄ ÍÀ ÏÐÎÁËÅÌÓ Ñàââî Â.Ì., Êèñåëåâà Ë.Ï. VIRUSES AND AUTOIMMUNE RHEUMATIC DISEASE. LOOKING FOR PROBLEM Savvo V.M., Kyselyova L.P. In this
article is summaries some of the areas of current research that may
eventually clarify he mechanism by which infectious agents could act as
the inciting agents of autoimmune rheumatic disease. Authors tried to
assess mechanisms of viral pathogenesis in rheumatic disease by
focusing on known viruses capable of causing inflammatory arthritis
syndromes and comparing virally induced immunological aberrations
with those noted in rheumatic disease patients. The experimental
evidence shows immunological cross reactivity between autoantigens and
viruses. Proteins of commonly occurring viruses have profound effects
on the cytokine, antigen recognition and lymphocyte cell survival.
Molecular mimicry and immunomodulation by viruses proteins may account
for both cross reactivity with autoantigens and abnormal T and B cell
functions in autoimmune disorders.
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5-10 |
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| ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ
ÐÎÁÎÒÈ (EXPERIMENTAL STUDY) |
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ÇÍÀ×ÈÌÛÅ ÊËÈÍÈÊÎ-ËÀÁÎÐÀÒÎÐÍÛÅ ÊÐÈÒÅÐÈÈ ÄÈÀÃÍÎÑÒÈÊÈ ÑÌÅØÀÍÍÛÕ
ÌÈÊÎÏËÀÇÌÎ-ÃÅÐÏÅÑÂÈÐÓÑÍÛÕ ÈÍÔÅÊÖÈÉ Ó ÁÎËÜÍÛÕ Ñ ÂÎÑÏÀËÈÒÅËÜÍÛÌÈ
ÇÀÁÎËÅÂÀÍÈßÌÈ ÃÎÐÒÀÍÈ Ïàí÷åíêî Ë.À., Êóëèêîâà Å.À., Ïîïîâà Í.Ã., Êèðè÷åíêî È.È., Ïîïîâà Ë.À., Âàñèíà Ñ.È., Çâÿãîëüñêàÿ È.Í., Ëè÷êî Â.À., Êîðîâàåâà È.Â. THE MAIN CLINACAL LABORATORY DIAGNOSTIC CRITERIONS FOR THE MIXED MYCOPLASMA AND HERPESVIRAL INFECTIONS ASSOCIATION IN PATIENTS WITH THE ACUTE LARYNGEAL DISEASES Panchenko L.A., Kulikova E.A., Popova N.G., Kirichenko I.I., Popova L.A., Vasina S.I., Zvyagolskaya I.N., Lichko V.A., Kîrîvaeva I.V. Association
of mycoplasma and herpesviruses with high level contamination was
established (91,7 % and 67,5 % for acute and chronic laryngitis course
accordingly) after serological examination of the 52 patients with the
acute laryngeal disease. The basic clinic laboratory diagnostic
criterions of the mixed infections were been prolonged acute
inflammatory process in larynx and its relapses to 3-4 time in a year
and high level of Ig M and Ig G for herpes and mycoplasma. Besides main
disease's symptoms in the patients was been weakness, sweating, not
infrequently prolonged subnormal body’s temperature and neck’s
lymphadenitis.
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11-14 |
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| ÔÀÃÎÖÈÒÀÐÍÀ
ÀÊÒÈÂͲÑÒÜ ÍÅÉÒÐÎԲ˲ ÏÅÐÈÔÅвÉÍί ÊÐβ ÒÀ ÌÀÊÐÎÔÀòÂ
ÁÐÎÍÕÎÀËÜÂÅÎËßÐÍÎÃÎ ËÀÂÀÆÓ ÏÐÈ ÏÍÅÂÌÎÍ²É Ð²ÇÍί ÅÒ²ÎËÎò¯ Â
ÅÊÑÏÅÐÈÌÅÍÒ² Êîëÿäà Ò.²., Áðóñí³ê Ñ.Â., Ìèõàéëè÷åíêî Ì.Ñ.,Íåñòåðåíêî À.Ì., Êîëÿäà Î.Ì. PHAGOCYTIC ACTIVITY OF PERIPHERAL BLOOD NEUTROPHILS AND BRONCHOALVEOLAR LAVAGE MACROPHAGES IN EXPERIMENTAL PNEUMONIA OF DIFFERENT ETIOLOGY Kolyada T.I., Brusnik S.V., Mikhailichenko M.S., Nesterenko A.M., Kolyada O.M. Nosocomial
pneumonia is an important problem and is one of the leading causes
of mortality from infectious diseases. The immune response in
course of pneumonia, especially the non specific resistance features,
is pathogen-specific and differs depending on the type of the causative
agent of pathologic processes in the lung. The staphylococcal
inflammatory process in the lung is accompanied by an increase in the
phagocytic activity of blood neutrophiles and bronchoalveolar lavage
macrophages. On the contrary, candicidal inflammation is characterized
by the decrease in these parameters. The most pronounced and stable
decrease in phagocytic activity was observed in animals with
inflammation caused by mixed infection.
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15-22 |
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| ÂÈÄÎÂÈÉ
ÑÊËÀÄ, ÏÎÏÓËßÖ²ÉÍÈÉ Ð²ÂÅÍÜ ÒÀ ÀÍÒÈÁ²ÎÒÈÊÎ×ÓÒËȲÑÒÜ Ì²ÊÐÎÔËÎÐÈ ÂÈIJËÅÍÜ
Ç ÓÐÅÒÐÈ ÕÂÎÐÈÕ ÍÀ ÕÐÎͲ×ÍÈÉ ÁÀÊÒÅвÀËÜÍÈÉ ÓÐÅÒÐÈÒ ×ÎËβʲ Ñèäîð÷óê Ë.²., Àâ人âà Ë.Â., Ñèäîð÷óê À.Ñ. SPECIES COMPOSITION, POPULATION LEVEL AND SENSITIVITY TO ANTIBIOTICS OF MICROFLORA OF URETHRAL SECRETIONS OF MEN THAT ARE SICK WITH CHRONIC BACTERIAL URETHRITIS Sydorchuk L.I., Avdeeva L.V., Sydorchuk A.S. It has
been conducted the investigation of species composition, population
level sensitivity to antibiotics of representatives of microflora of
secretions from urethra of 107 men that are sick with chronic bacterial
urethritis. It has been established that more often microflora of
urethral secretion of them are introduced by associations, which are
formed by three specieses of microorganisms, among them the leading
role have gonococcus, goldish staphylococcus, E. coli The leading
causative agents of chronic bacterial urethritis were mostly sensitive
to Ofloxacinum, Ceftriaxon, Doxycycline and Ciprofloxacin.
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| ÄÎÑ˲ÄÆÅÍÍß ÀÍÒÈ̲ÊÐÎÁÍί ÀÊÒÈÂÍÎÑÒ² ÒÀÁËÅÒÎÂÀÍÈÕ ÀÍÒÈÑÅÏÒÈ×ÍÈÕ ÏÐÅÏÀÐÀҲ Æîðíÿê Î. ². ANTIMICROBIAL ACTIVITY INVESTIGATION OF ANTISEPTIC TABLETS Zhornyak O. I.
Antimicrobial activity of antiseptic tablets results which have been obtained during experimental investigation under condition with different hydrogen ion concentration (pH) and microbial loading, have been given in this article. It has been detected domestic medicine septefril has high antimicrobial activity and differs advantageously from its similar medicine producted in other import manufactured in relation "price-quality".
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32-37 |
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| ÂÈÂ×ÅÍÍß ÐÎÑÒÎÂÈÕ ÂËÀÑÒÈÂÎÑÒÅÉ ÏÎÆÈÂÍÈÕ ÑÅÐÅÄÎÂÈÙ ²Ç ÇÅÐÍÎÂί ÁÀÐÄÈ Â²ÄÍÎÑÍÎ ÒÅÑÒ-ØÒÀ̲ ̲ÊÐÎÎÐÃÀͲÇ̲ Îñîëîä÷åíêî Ò.Ï., Âîëÿíñüêà Í.Ï.,Áàòðàê Î.À., Çàâàäà Í.Ï., Ïîðò Î.Â., Ðÿáîâà ².Ñ., Øòèêåð Ë.Ã. , Ïîíîìàðåíêî Ñ.Â. GROWS PROPERTIES OF NUTRIENT MEDIA OF GRAIN BARDA IN RESPECT OF TEST-MICROORGANISMS Osolodchenko T.P., Volyanska N.P., Batrak E.A., Zavada N.P., Port E.V., Ryabova I.S., Shtiker L.G. The woks
represents the research results of nutrient media from the grain barda.
The inoculation of media by small amounts of microorganisms grows
properties of nutrient. The estabblishment preservation of typica
culture and morphological properties, nutrient media of grain
barda for culture
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38-41 |
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| ÈÇÌÅÍ×ÈÂÎÑÒÜ ÔÀÊÒÎÐΠÏÀÒÎÃÅÍÍÎÑÒÈ ÇÎËÎÒÈÑÒÎÃÎ ÑÒÀÔÈËÎÊÎÊÊÀ ÏÎÄ ÂËÈßÍÈÅÌ ÓËÜÒÐÀÔÈÎËÅÒÀ Êðèâîõèæàÿ Ì.Â., Íàâðóëèí Â.Î., Êàëèíè÷åíêî Å.Î., Âîðîáüåâà Ë.È. VARIABILITY OF STAPHYLOCOCCUS AUREUS PATHOGENICITY FACTORS UNDER THE INFLUENCE OF ULTRAVIOLET Kryvohizhaya M.V., Navrulin V.O., Kalinichenko O.O., Vorob'yeva L.I. Ultraviolet
radiation is widely used for air disinfection facilities at special
medical institutions. Therefore, studying the effects of UV radiation
on pathogenic factors of aggression and shareware pathogenic
microorganisms is important for resolving of medical and biological
applied problems. Found that after exposure of UV radiation in some
isolates changed pigment synthesis, production of letsitinazy and
activity of plazmokoahulazy. The emergence of mutants could trouble the
identification of pathogenic strains of staphylococcus and cause
mistaken diagnostic conclusions.
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42-48 |
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| ²ñòîð³ÿ íàóêè (History of science) |
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| ÀÍÒÐÎÏÎËÎÃÈ×ÅÑÊÈÅ ÈÑÑËÅÄÎÂÀÍÈß È.È. ÌÅ×ÍÈÊÎÂÀ  ÈÑÒÎÐÈÈ ÑÅÊÑÎËÎÃÈÈ ÕIÕ — ÕÕ ÂÅÊΠ(Ê 165-ËÅÒÈÞ ÑÎ ÄÍß ÐÎÆÄÅÍÈß) ×óãóíîâ Â.Â. ANTHROPOLOGICAL STUDIÅS BY I.I. MECHNIKOV’S IN HISTORY OF MEDICAL SEXOLOGY IN CENTURY XIX — ÕÕ (TO 165TH ANNIVERSARY) Chugunov V.V. The
article reconstructs the formation of anthropological studies in
medical sexology in XIX-th — ÕÕ-th century. The prominent role of I.I.
Mechnikov in cognition and expansion of knowledge about realisation of
the macrobiological law of the form maintenance by the behavioral
displays (reactions) of man it is shown. The I.I. Mechnikov’s main
propositions by the proof of «disharmony» of human sexuality at all
levels of its regulation at different age periods were. Analyzed the
ethno-cultural, ethological, biological reasons which guided the author
in his anthropological research in sexology.
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49-52 |
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| ÈËÜß ÈËÜÈ× ÌÅ×ÍÈÊÎÂ: ÁÈÎÃÐÀÔÈ×ÅÑÊÈÅ, ÍÀÓ×ÍÛÅ È ÏÑÈÕÈÀÒÐÈ×ÅÑÊÈÅ ÀÑÏÅÊÒÛ (Ê 165-ËÅÒÈÞ ÑÎ ÄÍß ÐÎÆÄÅÍÈß) Ïåòðþê Ï.Ò. , Êó÷ìà È.Þ, Ðåçíèê Â.È. ILYA ILICH MECHNIKOV: BIOGRAPHIC, SCIENTIFIC AND PSYCHIATRIC ASPECTS (TO 165-TH ANNIVERSARY) Petriyuk P.T.,Kukhma I.Yu., Reznik V.I.
On the basis of sources of the special literature new information data is resulted about the biographic, scientific and psychiatric aspects of vital way of professor I.I. Mechnikov – famous scientist, philosopher, domestic home, native zoologist, biologist, physiologist, microbiologist, immunologist and pathologist, which what ponderable payment brought in the scientific achievements in development of domestic home,native and world science. The questions of psychiatric aspect, which had certain definite influence on the vital and creative ways of prominent remarkable scientist, are lighted up.
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53-62 |
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