Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-4 |
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ÎÃËßÄÈ (REVIEWS) |
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ÌÎËÅÊÓËßÐÍÎ-ÃÅÍÅÒÈ×Ͳ ÌÅÒÎÄÈ ÂÍÓÒ-вØÍÜÎÂÈÄÎÂÎÃÎ ÅϲÄÅ̲ÎËÎò×ÍÎÃÎ ÒÈÏÓÂÀÍÍß ÇÁÓÄÍÈʲ ²ÍÔÅÊÖ²ÉÍÈÕ ÇÀ-ÕÂÎÐÞÂÀÍÜ (ÎÃËßÄ) Òèì÷åíêî Î.Ì. MOLECULAR-GENETIC METHODS OF INTRASPECIFIC EPIDEMIOLOGICAL TYPING OF INFECTIOUS PATHOGEN AGENTS (REVIEW) Timchenko O.M. A
classification of methods intraspecific epidemiological genotyping of
infectious pathogen agents is presented. The classification is based on
technology of the methods reproduction, genetic characteristics of
strains, which are typing, and scope of the use of each method.
Key words: epidemiological pheno- and genotyping, molecular epidemiology, infectious pathogen agents |
5-7 |
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| ÒÈÐÅÎÈÄÍÛÉ ÑÒÀÒÓÑ ÎÐÃÀÍÈÇÌÀ È ÎÊÑÈÄ ÀÇÎÒÀ Áîíäàðü Ò.Í. AN ORGANISM THYROID STATUS AND NITRIC OXIDE Bondar T.8. Cardiovascular
complications at hypo-and hyperthyroidism are connected with
disfunction of vascular endothelium which key regulator is nitric
oxide. Data about sources of synthesis, nitric oxide physiological
effects, mechanisms of regulation of NO-syntases activity are
presented. Possible mechanisms of changes of NOsyntases activity at
hypo- and hyperthyroidism are discussed.
Key words: thyroid hormones, nitric oxide, vascular endothelium. |
8-12 |
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ÐÎÁÎÒÈ (EXPERIMENTAL STUDY) |
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ÏÈÙÅÂÎÉ ÍÀÃÐÓÇÊÈ Â ÏÎÑÒÍÀÒÀËÜÍÎÌ ÏÅÐÈÎÄÅ ÍÀ ÑÎÑÒÎßÍÈÅ
ÏÐÎÎÊÑÈÄÀÍÒÍÎ-ÀÍÒÈÎÊÑÈÄÀÍÒÍÎÉ ÑÈÑÒÅÌÛ ÊÐÎÂÈ ÊÐÛÑ ÏÐÈ ÈÌÌÓÍÈÇÀÖÈÈ
ÀÄÑ-ÀÍÀÒÎÊÑÈÍÎÌ Âîëÿíñêèé À.Þ., Íèêèò÷åíêî Þ.Â., Ñèìèðåíêî Ë.Ë.,Êó÷ìà È.Þ., Äàâûäåíêî Ì.Á. THE INFLUENCE OF ALIMENTARY LOAD IN POSTNATAL PERIOD OH THE STATE OF PROOXIDANT-ANTIOXIDANT SYSTEM OF RAT BLOOD UNDER IMMUNIZATION BY ADT ANATOXIN Volyansky A.Yu., Hikitchenko J.V., Simirenko L.L., Kuchma I.Yu., Davidenko M. B. The
influence of overnutrition in early postnatal period on the state of
prooxidant-antioxidant system of bloodunder immunization of Wistar rats
by ADT-anatoxin was investigated. The lowering of reliability of
enzymatic antioxidant system conditioned by
the decrease of seleniumdependent glutathione
peroxidase activity was revealed in blood of experimental
animals. It was shown that in the
process of formation of immune
response to diphtheria and tetanus anatoxins of ADT-vaccine
the content ofenzymatically active ceruloplasmin in experimental rats
was increased at more early stages compared with control rats.
Key words: prooxidant-antioxidant balance, ADTanatoksin, rats, overnutrition.
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13-16 |
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| HUMAN HERPESVIRUS TYPE 6 AND ITS INFECTION LEVEL AT THE PATIENTS WITH LARYNGOPHARYNGEAL DISEASE Panchenko L.A., Popova N.G., Torianyk I.I., Kazmirchuk V.V. High
level of infection with type 6
human herpesvirus (69,2%) was established
in patients with infectious inflammatory
diseases of the pharynx and larynx.
Increased level of Ig G antibodies simultaneously to HSV and HHV-6 was
determined in 38,0 % of cases.
Key words: herpes simplex virus, human herpesvirus type 6, laryngitis, pharyngitis, infectious. |
17-19 |
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| ÂÏËÈ ÊÎÌÁ²ÍÎÂÀÍί IJ¯ ÑÒÈÌÓËßÒÎв ղ̲×ÍÎÃÎ ÏÎÕÎÄÆÅÍÍß ÍÀ ØÂÈÄʲÑÒÜ ÏÐÈÐÎÑÒÓ Ì²ÊÐÎÁÍί ÌÀÑÈ PSEUDOMONAS AERUGINOSA Ìàðòèíîâ À.Â., ×óïðèíîâà Ñ.²., Îñîëîä÷åíêî Ò.Ï., Áàòðàê Î.À., Çàâàäà Í.Ï., Ðÿáîâà ².Ñ., Øòèêåð Ë.Ã. INFLUENCE OF THE CHEMICAL ENCHANCERS COMBINED ACTION ON GROWTH OF MICROBAL MASS OF PSEUDOMONAS AERUGINOSA Martynov A.V., Chuprinova S.I., Osolodchenko TP., Batrak E.A., Zavada N.P.. Ryabova I.S, Shtiker l.G. The
chemical growth factors (enhancers) joint influence is studied on speed
of microbal mass growth of Pseudomonas aeruginosa. Experimentally
well-proven the expressed stimulant influence due to the combined
action of isochinolin’s and imidasol’s derivatives on biological
properties of P. aeruganosa
Keywords:nourishing environment, growth factors, Pseudomonas aeruginosa |
20-24 |
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| Á²ÎËÎò×ÍÀ ÕÀÐÀÊÒÅÐÈÑÒÈÊÀ ÀÍÒÈÃÅͲ ÇÁÓÄÍÈÊÀ ÄÈÔÒÅв¯, ÂÈIJËÅÍÈÕ ÇÀ ÄÎÏÎÌÎÃÎÞ Ô²ÇÈÊÎ-ղ̲×ÍÈÕ ÌÅÒÎIJ ªëèñåºâà ².Â., Áàáè÷ ª.Ì., Æäàìàðîâà Ë.À., Á³ëîçåðñüêèé Â.²., Ãîðáà÷ Ò.Â., Êîëïàê Ñ.À., Áîáèðºâà ².Â. BIOLOGICAL CHARACTERISTICS OF DIPHTHERIAE PATHOGEN ANlTIGENS OBTAINED BY PHYSICOCHEMICAL METHODS Yelyseyeva I.V., Babych Ye.M., Zhdamarova L.A., Belozersky V.I., Kolpak S.A., Gorbach T.V., Bobireva I.V. Conducted
study covers development of approaches to diphtheria vaccine
improvement notably referred to increase of antibacterial immunity as a
factor of diphtheria infection localization in a humane organism.
Physicochemical factors are used for obtaining of native pathogen
antigens. At the first stage of the study the most perspective regime
of the microbe cells ultrasonic disintegration, use of chemical agents
and ultra filtration are taken for antigen preparations obtaining with
the potentially most effective immunogenic and adjuvant properties. A
description of the obtained specimens of antigenic
fractions preparations on chemical composition and molecular weight is represented. Keywords: diphtheria, vaccine, ultrasonic |
25-31 |
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| ×ÓÒËȲÑÒÜ ÓÌÎÂÍÎ-ÏÀÒÎÃÅÍÍÈÕ ÁÀÊÒÅÐ²É ÄÎ ÄÈÔÒÅвÉÍÎÃÎ ÒÎÊÑÈÍÓ ÏÐÈ ÇÀÑÒÎÑÓÂÀÍͲ ̲˲ÌÅÒÐÎÂÈÕ ÕÂÈËÜ Áàáè÷ ª.Ì., Êàë³í³÷åíêî Ñ.Â., ʳââà Ô.Â. , Âîëÿíñüêèé Þ.Ë., Ðèæêîâà Ò.À., Êîâàëåíêî Î.². Æäàìàðîâà Ë.À. , Øêîäîâñüêà Í.Þ., Áîáèðåâà ².Â. THE SENSITIVITY OF OPPORTUNISTIC PATHOGENIC BACTERIA TO DIPHTHERIA TOXIN BEFORE AND AFTER MILLIMETER WAVES IRRADIATION Babych E.M., Kalinichenko S.V., Kivva F.V., Volajnskyj Yu.L. , Ryzhkova T.A. , Kovalenko O.I., Zhdamarova L.A., Shkodovska N.Yu., Bobyreva I.V. The growth
kinetics of microorganisms under influence of the different
doses of diphtheria toxin before
and after using millimeters waves
determined frequency ranges (40,0 HHz;
42,2 HHz; 50,3 HHz; 58,0 HHz;
61,0 HHz; 64,5 HHz) was studied. It
was found experimentally that after adding diphtheria
toxin in nutrient medium inamount 0,1 ml on 1,0 ml ambiences the
growing of S.aureus ATCC 25923 was suspended but
the accumulation of E.faecalis ATCC
6783microbial mass was stimulated. The presence of 0,3
ml diphtheria toxin in 1,0 ml
nutrient medium resulted to enterococcus
growth inhibition and partial S.aureus lysis.
It was determined that adding diphtheria
toxin irradiated in different frequency range of millimeter waves
in nutrient medium brought to the
differently directed changes in the growth kinetics of microorganisms
which depended of amount of the
toxin, frequencies of millimeter waves and type used for
experiment bacteria.
Key words: opportunistic pathogenic bacteria, growth kinetics, diphtheria toxin, millimeters waves. |
39-42 |
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