Ç̲ÑÒ (Contents)
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Ðåäàêö³éíà ðàäà (Editorial Board) |
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Çì³ñò (Contents) |
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ÎÃËßÄÈ (REVIEWS) |
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| ÏÅÐÑÏÅÊÒÈÂÛ È ÏÓÒÈ ÐÀÇÂÈÒÈß ÏÐÎÈÇÂÎÄÑÒÂÀ
ÁÈÎÒÅÕÍÎËÎÃÈ×ÅÑÊÈÕ ËÅÊÀÐÑÒÂÅÍÍÛÕ ÏÐÅÏÀÐÀÒΠ ÓÊÐÀÈÍÅ Ñòðåëüíèêîâ Ë. Ñ., Ñòðèëåö Î. Ï., Ùåðáàê Å. Â., ×èêèòêèíà Â. Â., Äîëãîâà Ò. À. PERSPECTIVES AND DEVELOPMENT PRODUCTION OF BIOTECHNOLOGICAL DRUGS IN UKRAINE Strelnikov L.S., Strilets O.P., Shcherbak E.V., Chicitkina V.V., Dolgova T.A. This
article presentation the modern situation and perspectives of
pharmaceutical biotechnology in the world and the Ukraine. In the
article are discussion perspectives applications of biotechnology
methods for production the drugs. Advantage these preparations are low
cost and don’t have any side-effect.
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3-8 |
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| ÅÊÑÏÅÐÈÌÅÍÒÀËÜͲ ϲÄÕÎÄÈ ÄÎ ÑÒÂÎÐÅÍÍß
ÅÍÒÅÐÀËÜÍÈÕ ÔÎÐÌ ÏÐÎÒÈÄÈÔÒÅвÉÍÈÕ ÏÐÅÏÀÐÀҲ Á³ëîçåðñüêèé Â.²., Áàáè÷ ª.Ì., Âîëÿíñüêèé Þ.Ë., Êðàñíîïîëüñüêèé Þ.Ì., Ùåò³í³íà Â.Ì., Êîëîêîëîâà Î.Á., Âåðåçóá Ë.Ã., Ìàðòèíîâ À.Â., Æäàìàðîâà Ë.À., Ñêëÿð Í.²., ×óºøîâ Â.². EXPERIMENTAL APPROACHES TO CREATION OF ENTERAL FORMS OF ANTIDIPHTHERITIC PREPARATIONS Belozersky V.I., Babich E.M., Volansky Y.L., Krasnopolsky Y.M., Chetinina V.M., Kolokolova O.B., Verezub L.G., Martinov A.V., Zhdamarova L.A., Sklar N.I., Chuyeshov V.I. The data
of study of immogenic properties of somatic antigens of Corynebacterium
diphtheria protected by different polymer combinations at different
methods of application are presented. More expressed immunogenity of
liposomal forms of antigen at introduction per os to experimental
animals at background of preliminary parenteral in-troduction of this
preparation is demonstrated. The conclusion about the perspective of
improvement of immunization shemes with utilization of effective doses
and optimal intervals between the introduction of preparations.
Key words: liposomal and modificated forms of antigens; Corynebacterium diphtheriae, revaccination, ground-immunity, humoral immnity, antibodies. |
9-13 |
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| ÂÏËÈ ÀÄÏ-ÀÍÀÒÎÊÑÈÍÓ ÍÀ ÃËÞÊÎÊÎÐÒÈÊίÄÍÈÉ
ÑÒÀÒÓÑ ÙÓв вÇÍÎÃΠ²ÊÓ Âîëÿíñüêèé À.Þ. THE INFLUENCE OF ADT-ANATOXIN ON GLUCOCORTICOID STATUS OF RATS OF DIFFERENT AGE Volyanskiy A.Y. We
examined the age-specific glucocorticoid status characteristics of
intact male rats line Wistar aged 3 an 30 months during the
immunization with ADT-anatoxin. The age-specific features of
glucocorticoid function GG ACS functional state and the age-related and
specific differences of anti-diptheria and anti-tetanus antibody
genesis during the antitoxic immune response development process were
identified. The empirical mathematical models of body glucocorticoid
status changes in the dynamics of formation process of the antitoxic
immune response are received depending on term after immunization and
age of animals.
Key words: corticosterone, rats, immunization, antibody genesis, ADT-anatoxin.
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14-22 |
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| ÄÒÅÕÍÎËÎÃ²ß ÎÄÅÐÆÀÍÍß Ð²ÄÊÎÃÎ ÏÐÎÁ²ÎÒÈÊÓ Ç
ÀÅÐÎÊÎʲ Ðèæåíêî Ñ.À., Êðåìåí÷óöüêèé Ã.Ì. , Áðåäèõ³íà Ì.Î., Äèêëåíêî
Ò.Â., Äðîáîò Î.Â., Ñòåïàíñüêèé Ä.Î., Õ³ëüêî Ë.Â., Âàëü÷óê Ñ.²., Þðãåëü
Ë.Ã., Êîíäðàòüºâ À.Þ., Êîøåâà ².Ï. TECHNOLOGY OF CREATION OF LIQUID PROBIOTIC
FROM AEROCOCCI
Rijenko S.A., Kremenchutsky G.N., Bredichina M.O., Diklenko T.V., Drobot O.V., Stepansky D.A., Chilko L.V., Valchuk S.I., Urgel L.G., Kondratiev A.U., Koshevaya I.P. The dynamics of growth of culture of production culture of A.v³r³dans N 167 on different nourishing environments and an optimum nourishing environment is select for the receipt of liquid form of probiotics «A-bacterinum». Possibility of constructing of liquid forms of probiotics is experimentally well-proven taking into account the biochemical aspects of metabolism of probiotics cultures and by the observance of principles and requirements FAO/WHO. On the basis of the received data the basic technological scheme of manufacture of the liquid form of a probiotic is developed «A-bacterinum». |
23-28 |
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| ÏÅÐÑÈÑÒÈÐÓÞÙÈÅ ÃÅÐÏÅÑÂÈÐÓÑÛ ÊÀÊ
ÏÎÒÅÍÖÈÀËÜÍÛÉ ÒÐÈÃÅÐ-ÔÀÊÒÎÐ ÑÎÌÀÒÈ×ÅÑÊÈÕ ÇÀÁÎËÅÂÀÍÈÉ Ñìåëÿíñêàÿ Ì.Â., Ïåðåìîò Ñ.Ä., Ìàðòûíîâ À.Â. PERSISTENT HERPESVIRUSES AS POTENTIAL TRIGGER-FACTOR OF SOME SOMATIC DISEASES Smelyanskaya M.V., Peremot S.D., Martynov A.V. Obtained
results shown that in human’s organism, especially with chronic somatic
pathology, were presented persistent viruses of herpes group in one or
more organs with big probability. Presence persistent viruses of herpes
group in one or more human’s organs can start mechanism of reactivation
of persistent infection, caused by herpes virus with involved in
infectious process other not herpes group viruses. Besides after
infected by herpes virus of host organism the related virus from other
group are possible caused of they exaltation action.
Key words: herpesviruses, persistence, somatic patology. |
29-33 |
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| ÄÈÎÊÑÈÄ ÕËÎÐÀ ÊÀÊ ÑÐÅÄÑÒÂÎ ÏÐÎÔÈËÀÊÒÈÊÈ
ÍÎÇÎÊÎÌÈÀËÜÍÛÕ ÈÍÔÅÊÖÈÉ Ìîêèåíêî À.Â., Ïåòðåíêî Í.Ô., Ãîæåíêî À.È., Ïîíîìàðåíêî À.Í. CHLORINE DIOXIDE AS AN AGENT OF PROPHYLAXIS OF NOSOCOMIAL INFECTION Mokienko A. V., Petrenko N. F., Gozhenko A. I., Ponomarenko A.N. In work
some given literatures on interrelation microbial contaminations of
water and flares of nosocomial infection are submitted. The necessity
of a padding decontamination of water submitted in hospitals is proved.
The assumption of an opportunity of application for this purpose of
chlorine dioxide as high performance desinfectant is stated.
Key words: chlorine dioxide, desinfection of water, nosocomial infection, prophylaxis |
25-29 |
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| ÏÐÈÌÅÍÅÍÈÅ ÌÅÒÎÄÈÊÈ ÊËÎÍÈÐÎÂÀÍÈß ÊËÅÒÎÊ
ÑÒÐÎÌÛ ÊÎÑÒÍÎÃÎ ÌÎÇÃÀ ×ÅËÎÂÅÊÀ ÄËß ÈÇÓ×ÅÍÈß (IN VITRO) ÏÐßÌÎÃÎ ÄÅÉÑÒÂÈß
ÝÍÄÎÃÅÐÌÅÒÈÊΠÀñòàõîâà Â.Ñ., Ïàí÷åíêî Ë.Ì. USING OF CLONING METHODS FOR DISCOVERING THE INFLUENCE OF ENDOGERMETICS ACTION ON STROMA CELLS (IN VITRO) Astahova V.S., Panchenko L.M. The
results of investigation of cytotoxic influence of materials for root
canals feeling by cells-cultivating method are described in the
article.
Key words: cells-cultivating method, fibroblasts, cytotoxic fluence, materials for root canals feeling. |
38-44 |
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| ÐÀÇÐÀÁÎÒÊÀ ÈÍÄÈÂÈÄÓÀËÜÍÛÕ ÑÕÅÌ ÏÐÈÌÅÍÅÍÈß
ÏÐÎÒÈÂÎÌÈÊÐÎÁÍÛÕ ÏÐÅÏÀÐÀÒÎÂ ÏÐÈ ÂÎÑÏÀËÈÒÅËÜÍÛÕ ÏÀÒÎËÎÃÈßÕ ÊÎÆÈ È
ÑËÈÇÈÑÒÛÕ Ó ÑÎÁÀÊ ÍÀ ÎÑÍÎÂÅ ÐÅÇÓËÜÒÀÒΠÈÇÓ×ÅÍÈß ÑÂÎÉÑÒ ÂÛÄÅËÅÍÍÎÉ
ÌÈÊÐÎÔËÎÐÛ Îáóõîâñêàÿ Î.Â., Ñòåãíèé Á.Ò., Êåëåáåðäà Í.È., Ãëåáîâà Ê.Â. DEVELOPMENT OF INDIVIDUAL CHARTS OF APPLICATION OF ANTIBACTERIAL PREPARATIONS AT INFLAMMATORY PATHOLOGIES OF SKIN AND MUCOUS MEMBRANES FOR DOGS ON BASIS OF RESULTS OF STUDY OF PROPERTIES OF SELECTED MIKROFLORY Obuchovskaya O.V., Stegniy B.T., Keleberda N.I., Glebova K.V. During
conducting of bacteriological study of pathological material from dogs
with different pathologies (dermatitises, vaginits, postits,
conjunctivitises, otitides and stomatits) isolated and studied 205
cultures of microorganisms. It is set that gram+ cocci (representatives
of births of Staphylococcus, Streptococcus and Micrococcus) and
enterobakterys (representatives of Proteus, Citrobacter and Serratia)
have most etiologic value, which in 81,46 % cases selected in
composition bacterial associations. The sensitiveness of the selected
cultures is studied to the basic groups of antibiotics. Methodical
approaches are certain to development of individual charts of treatment
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38-41 |
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| Òåçè
äîïîâ³äåé íàóêîâî-ïðàêòè÷íî¿ êîíôåðåíö³¿ ç ì³æíàðîäíîþ ó÷àñòþ «Ïîøóê òà
ðîçðîáêà íîâèõ ïðîô³ëàêòè÷íèõ ³ ë³êóâàëüíèõ ïðîòèì³êðîáíèõ çàñîá³â,
àíòèñåïòèê³â, äåç³íôåêòàíò³â òà ïðîá³îòèê³â», 20-21.11.2006 |
41-174 |
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