Ç̲ÑÒ (Contents)
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C. (P.) |
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Ðåäàêö³éíà ðàäà (Editorial Board) |
1 |
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Çì³ñò (Contents) |
2-4 |
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ÎÃËßÄÈ (REVIEWS) |
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| ÒÅÇÈ ÄÎÏβÄÅÉ XV Ç’¯ÇÄÓ Ì²ÊÐÎÁ²ÎËÎòÂ, ÅϲÄÅ̲ÎËÎòÂ, ÏÀÐÀÇÈÒÎËÎò ÓÊÐÀ¯ÍÈ «ÏÐÎÁËÅÌÈ ÒÀ ÅÂÎËÞÖ²ß ÅϲÄÅ̲×ÍÎÃÎ ÏÐÎÖÅÑÓ ² ÏÀÐÀÇÈÒÀÐÍÈÕ ÑÈÑÒÅÌ ÏÐβÄÍÈÕ ²ÍÔÅÊÖ²É ÑÓ×ÀÑÍÎÑÒ²», 23-25 ËÈÑÒÎÏÀÄÀ 2011 Ð., Ì. ÕÀÐʲ ABSTRACTS XV Congress of microbiologists, epidemiologists, parasitologists Ukraine "Problems and Evolution epidemic process and parasitic systems Infections Leading the Present" on 23-25 November 2011, Kharkov
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6-240 |
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| ÂÏËÈ ÅËÅÊÒÐÎÌÀÃͲÒÍÎÃÎ ÏÎËß ÀÍÒÐÎÏÎÃÅÍÍÎÃÎ ÏÎÕÎÄÆÅÍÍß ÍÀ ÀÄÀÏÒÈÂÍÈÉ ÏÎ˲ÌÎÐÔ²ÇÌ Ì²ÊÐÎÁÀÊÒÅÐ²É Âëàñåíêî Â.Â., Âëàñåíêî ².Ã.,Âîëÿíñüêèé À.Þ. INFLUENCE OF ANTHROPOGENIC ELECTROMAGNETIC FIELDS ON THE ADAPTIVE MYCOBACTERIUM’S POLYMORPHISM Vlasenko V.V., Vlasenko I.G., Volyanskiy A. Yu. In this article the features of development of exciter of tuberculosis are lighted at the action of the electromagnetic
field of antropogenic origin subject to the condition in vitro. It is
shown that the microstructure of pathogenic of tuberculosis after
treatment an ionizing and unionizing irradiation is not violated, and
reproductive activity grows, that is confirmed the results of cultural
researches and electronic and computer microscopy.
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241-245 |
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| ÁÓÒÈ ×È ÍÅ ÁÓÒÈ ÏÀÒÎÃÅÍÎÌ: ̲ÊÐÎÁ²ÎÖÅÍÎÇ ÂÅÐÕÍ²Õ ÄÈÕÀËÜÍÈÕ ØËßÕ²Â, ԲDzÎËÎò×ÍÅ ÇÀÏÀËÅÍÍß ÒÀ ÎÁÐÀÇÐÎÇϲÇÍÀÞײ ÐÅÖÅÏÒÎÐÈ Êàìèøíèé Î.Ì., Âîéòîâè÷ Î.Â, Òîïîë ². Î., Äåãåí À.Ñ. TO BE OR NOT TO BE A PATHOGENS: MICROBIOCENOSIS OF UPPER RESPIRATORY TRACT, PHYSIOLOGICAL INFLAMMATION AND PATTERN RECOGNITION RECEPTORS Kamyshniy O. M., Voitovich O. V, Topol I. O., Degen A. S. This
review own data is dedicated to ability of macroorganism to adequate
response to the invasion of various microorganisms. The traditional
idea of indigenous or normal microflora, as a simple symbiotic
populations of microorganisms from different biotopes of the human past
decade has shattered and does not reflect its real biological
significance. However, the microflora is extremely sensitive to adverse
factors and changes its parameters can be indicated by such influences.
The main role in maintaining tolerance and initiate the immune response
is the innate immune factors. Determination of antigen is based on the
recognition of evolutionary highly conserved structures, called
microorganism-associated molecular images. In this review present
several hypotheses lower-level alarm on pattern-recognition receptors
as a result of their interaction with the microorganism-associated
molecular images of commensal microflora.
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246-251 |
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| Á²ÎÑÓ̲ÑͲ ÊÀËÜÖ²É-ÔÎÑÔÀÒͲ ÏÎÊÐÈÒÒß ÄËß ÌÅÒÀËÅÂÈÕ ²ÌÏËÀÍÒÀҲ Ñóõîäóá Ë.Á., Âîëÿíñüêèé À.Þ., Ñóõîäóá Ë.Ô., Ãóøèëèê Á.², Ãàéäó÷îê ².Ã., Êàçì³ð÷óê Â.Â., Øóëüãà Í.Ì., Ïîâîëîê³íà ².Â., Ïàðóñîâ À.Â. BIOCOMPATIBLE CALCIUM-PHOSPHATE COATINGS FOR METALIC IMPLANTS Sukhodub L.B., Volansky A.Yu., Sukhodub L.F., Guschilik B.I., Gayduchok I.G., Kazmirchuk V.V., Schulga N.M., Povolokina I.V., Parusov A.V. State and
perspective of the creation and investigation of biocompatible
calcium-phosphate coatings on metalic implants have been discussed in
the overview. The methods for obtaining these coatings, such as plasma
sputtering, biomimetic methods, electroforetic method, ion sputtering,
thermodeposition with a cooling system and others were considered. Some
perspective as for broadening of an action field of the coatings for
implants via incorporation into calcium-phosphate nanostructured
surface some specific bioactive molecules and drugs also are
discucced.
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252-257 |
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| Åêñïåðèìåíòàëüí³ ïðàö³ |
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| ÎÑÎÁËÈÂÎÑÒ² Ê˲Ͳ×ÍÎÃÎ ÏÅÐÅÁ²ÃÓ ² ØËßÕÈ ÓÄÎÑÊÎÍÀËÅÍÍß Ë²ÊÓÂÀÍÍß ÊÈØÊÎÂÈÕ ²ÍÔÅÊÖ²É Ó Ä²ÒÅÉ ÍÀ ÑÓ×ÀÑÍÎÌÓ ÅÒÀϲ Îëüõîâñüêà Î. Ì. SOME PECULIARITIES OF CLINICAL PICTURES AND WAYS OF IMPROVEMENT OF TREATMENT OF INTESTINAL INFECTIONS AT CHILDREN TODAY. Olkhovska O.N. The main
clinical peculiarities of Shigellosis, Salmonellosis, Escherichiosis at
420 yearly age children were performed. Its
characterized by hight percent of
gastroenterocolitic forms, vomiting,
ketoacidosis, and dehydratation on presentation. The clinical
values of ultrasonic investigations of haemodynamic indexes were
investigated. It was proposed to add ultrasonic haemodynamic indexes to
standards of treatment of severe form of intestinal infectious diseases
at children.
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258-261 |
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| ÀÍÒÈ̲ÊÐÎÁÍÀ ÀÊÒÈÂͲÑÒÜ ÅÊÎËÎò×ÍÎ ÁÅÇÏÅ×ÍÎÃÎ ÐÎÇ×ÈÍÓ ÍÀÍÎÑвÁËÀ, ÎÒÐÈÌÀÍÎÃΠղ̲×ÍÈÌ ÌÅÒÎÄÎÌ Ì³õ³ºíêîâà À.²., ͳêîíîâà Í.Î., Ðîìàíåíêî Ë.². ANTIMICROBIAL ACTIVITY OF ECOLOGICALLY SAFE SOLUTION OF NANO SILVER OBTAINED BY CHEMICAL METHOD Mikhienkova A.I., Nikonova N.A., Romanenko L.I. In
experimental investigation the antimicrobial activity of silver nano
particles (8-12 nm) in colloid solution and in the matrix of
high-dispersive silicon dioxide stabilized by the mixture of
polyvinylpyrrolidone and sodium dodecyl sulphate was studied. The
quantity of the latter one was decreased to the level of limited
permissible concentration. In result of conducted work it was proved
that obtained solution kept stability and the high antimicrobial effect
for test strains of E. coli and S. aureus: after 1-2 hours of
exposition the reduction of them for more than 5 lg was reached. The
obtained data allowed recommend studied solutions in the base of silver
nano particles for the use as ecologically safe preparations with
antimicrobial activity in the different fields of medicine, biology and
food industry.
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262-265 |
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| ÀÍÒÈÊÎÌÏËÅÌÅÍÒÀÐÍÀ ÀÊÒÈÂͲÑÒÜ ÏÐÅÄÑÒÀÂÍÈʲ ̲ÊÐÎÁ²ÎÖÅÍÎÇÓ ÒÎÂÑÒί ÊÈØÊÈ Ó ÕÂÎÐÈÕ ÍÀ ÐÅÂÌÀÒίÄÍÈÉ ÀÐÒÐÈÒ Êó÷ìàêÎ.Á., Êëèìíþê Ñ.². Anticomplementary activity of COLON microbicenosis REPRESENTATIVES IN PATIENTS WITH RHEUMATOID ARTHRITIS Kuchmak O.B., Klymnyuk S.I. The
classic bacteriological method was used for investigation of colon
microbiocenosis in 72 patients with rheumatoid arthritis at the age of
20 to 55 years. It was revealed that patients with rheumatoid arthritis
had dysbacteriosis mainly I (37,5%) and II (41,7%) degree. Some
populations of bacteria isolated from these patients had
anticomplementary activity that was most
prominent in gram-negative than in
gram-positive microorganisms. Lactobacillus rhamnosus GG probiotic
strain had a pronounced antagonistic activity against important
representatives of colon microbiocenosis: E. coli, Enterococcus spp.,
Klebsiella spp., S. aureus, but more than 60,0 % of clinical strains of
Pseudomonas aeruginosa were insensitive to the action of this
antagonist.
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266-270 |
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| ÑÎÄÅÐÆÀÍÈÅ ÖÈÒÎÊÈÍÎÂ È Ñ-ÐÅÀÊÒÈÂÍÎÃÎ ÏÐÎÒÅÈÍÀ  ÑÛÂÎÐÎÒÊÅ ÊÐÎÂÈ ÁÎËÜÍÛÕ ÕÐÎÍÈ×ÅÑÊÈÌ ËÀÐÈÍÃÈÒÎÌ C ÏÅÐÑÈÑÒÅÍÖÈÅÉ ÃÅÐÏÅÑÂÈÐÓÑÍÎÉ ÈÍÔÅÊÖÈÈ (ÂÏà 1-2 ÒÈÏÎÂ) Ãàðþê Ã.È., ÊóëèêîâàÅ.À., Çóåòèð Ñàìèð CYTOKINES AND C-REACTIVE PROTEIN CONTENT IN SERUM BLOOD OF PATIENTS WITH CHRONIC LARYNGITIS DISEASE GarjukG. I., KulikovaE.A., ZaetirSamir Some kinds
of interleikines and C-reactive protein of acute phase of patients with
chronic laryngitis disease were investigated. There is “cytokines
explosion” of the patients chronic laryngitis with persistent herpes
simplex virus. Comparative investigation cytokine profile in serum
blood demonstrated: balanced reaction cytokines profile of patients
chronic laryngitis without persistent herpes simplex virus and
dysbalanced reaction of patients laryngitis (hyperergation). Increased
content IL-6 and low content γ-interferon and tumor necrosis factor
(TNF-α) are predisposition of chronisation inflammation processes in
larynges. This situation needed in sighting correction.
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271-277 |
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| ÂÈÂ×ÅÍÍß ²ÍÔ²ÊÎÂÀÍÎÑÒ² ÕÂÎÐÈÕ ÍÀ ÄÎÁÐÎßʲÑÍÓ Ã²ÏÅÐÏËÀÇ²Þ ÏÅÐÅÄ̲ÕÓÐÎÂί ÇÀËÎÇÈ ( ÄÃÏÇ ), ÓÑÊËÀÄÍÅÍÓ ÒÀ ÍÅÓÑÊËÀÄÍÅÍÓ ÃÎÑÒÐÎÞ ÇÀÒÐÈÌÊÎÞ ÑÅײ Ðèìøà Î. Â. STUDY OF INFECTION OF PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA, COMPLICATIONS AND UNCOMPLICATED ACUTE URINARY RETENTION Rymsha O. V. The paper
presents the results of bacteriological studies of pathological
material from patients after surgery for BHPG. complications and no
complications of acute urinary retention. Material for the study were -
urine intraoperatively removed tissue of the prostate and prostate
secretion. Clinical isolates of microorganisms were characterized by
morphological, Cultural and biochemical properties. The greatest number
of complications and longest postoperative period were observed in
patients with chronic infection caused by gram flora. Frequency of
Gram-negative bacteria in the samples was 69.3%, gram-positive - 25%.
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278-280 |
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| ÈÇÓ×ÅÍÈÅ ÌÈÊÐÎÁÈÎÖÅÍÎÇÀ ÊÎÆÈ ÏÐÈ ÑÎÇÄÀÍÈÈ ÝÊÑÏÅÐÈÌÅÍÒÀËÜÍÎÉ ÌÎÄÅËÈ ÔËÅÃÌÎÍÛ Ó ÊÐÛÑ Ñêàêîâñêàÿ Î.È., Ñòåïàíñêèé Ä.À., Êðåìåí÷óöêèé Ã.Í., Äðîçäîâ À.Ë. IN THE STUDY OF MICROBIOCENOSIS OF SKIN AT CREATION OF EXPERIMENTAL MODEL OF PHLEGMON FOR RATS. Skakovskaya O.O., Stepansky D.O., Kremenchutsky G.N., Drozdov A.L. The
positive role of microorganisms of skin is well-known in maintenance of
health of macroorganism. A question about the role of
microorganisms of skin in development of phlegmon remains to the not
end studied. Understanding of conformities to law of change of microbal
landscape of skin at a festering-inflammatory defeat (to the phlegmon)
will allow considerably to optimize diagnostics and treatment of this
pathology. In this work the changes of microbal
landscape of skin of intact rats were appraised
and at the design of phlegmon. Heterogeneity of specific
composition of microflora of intact skin of white rats is rotined,
taking part in an experiment, which is presented saprophyte and
conditional-pathogenic microorganisms. Specific composition of
skin of rats changed during the design of phlegmon, new kinds appeared
( S. aureus, K. pneumoniae). In 7 % cases from the place of phlegmon
bacterial associations were selected, presented S. aureus, K.
pneumoniae and fungi.
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281-283 |
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| ÎÑÎÁËÈÂÎÑÒ² ÔÎÐÌÓÂÀÍÍß ÁÀÊÒÅвÀËÜÍÈÕ Á²ÎÏ˲ÂÎÊ ÍÀ ÏÎÂÅÐÕͲ ÕÎËÅÑÒÅÀÒÎÌ ÏÐÈ ÕÐÎͲ×ÍÈÕ ÃͲÉÍÈÕ ÑÅÐÅÄÍ²Õ ÎÒÈÒÀÕ Ìîãèë³âñüêà Í.Ì., Âîéöåõîâñüêèé Â.Ã., Ñóøêî Þ.Î., Áîðèñåíêî Î.Ì., Ñðåáíÿê ².À. FEATURES OF BACTERIAL BIOFILMS FORMING ON THE SURFACE OF CHOLESTETOMAS AT CHRONIC SUPPURATIVE OTITIS MEDIA Mogylivska N.M., Voytsehovskiy V.G., Soushko Yu O., Borysenko O.M., Srebnyak I.A. The
results of detection of microorganisms on the surface of cholesteatomas
and also from the exsudate of cavity of middle ear are presented in
this work. By the method of raster electronic microscopy on the surface
of cholesteatomas which removed during operations, had been found
bacterial biofilms, and through bacteriological researches were
isolated microorganisms of different species (S. åpidermidis, P.
àeruginosa, S. aureus, S. saprophyticus, E. coli, E. cloacae,
Micrococcus spp., Citrobacter spp., Corynebacterium spp.). Comparison
of bacteriological and electronic microscopic data has confirmed a
hypothesis that biofilms are not found by standard cultural methods. It
is necessary to carry out bacteriological studies of cholesteatomas,
removed during operations, for the purpose of improvement diagnostics
and prescription etiotropic antibiotic therapy.
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284-288 |
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| ÏÎÑÎÁÅÍÍÎÑÒÈ ÈÍÒÎÊÑÈÊÀÖÈÎÍÍÎÃÎ ÑÈÍÄÐÎÌÀ Ó ÁÎËÜÍÛÕ ÎÑÒÐÎÏÐÎÃÐÅÑÑÈÐÓÞÙÈÌ ÒÓÁÅÐÊÓËÅÇÎÌ ËÅÃÊÈÕ Ëåáåäü Ë.Â., Êèðååâ È.Â.*, Ïîòåéêî Ï.È., Ëÿøåíêî À.À. FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH ACUTELY PROGRESSIVE PULMONARY TUBERCULOSIS Lebid L.V., Kireyev I.V., Poteyko P.I., Liashenko A.A. The
features of intoxication syndrome in patients with acutely progressive
pulmonary tuberculosis during the epidemic of
tuberculosis in Ukraine. The analysis
is performed on two groups of
patients with acutely progressive pulmonary tuberculosis:
115 patients treated in a tuberculosis clinic in 1993-1995 and 100
patients treated in 2006-2009. For objective assessment of the severity
of intoxication syndrome was used test available -haematological
toxicity index, which was calculated for the clinical analysis of
blood. It is established that patients, treated in 2006-2009, had a
slower regression of intoxication syndrome. Studying the dynamics of
the haematological toxicity index in the dynamics after three and six
months of chemotherapy led to the conclusion about the need for
intensive detoxification, not only in patients with severe intoxication
syndrome, but also for weakly expressed.
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289-292 |
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ÏÅÐÑÏÅÊÒÈÂͲÑÒÜ ÂÈÊÎÐÈÑÒÀÍÍß ÏÐÎÒȲÐÓÑÍÈÕ ÇÀÑÎÁ²Â Ó ÊÎÌÏËÅÊÑÍ²É ÒÅÐÀϲ¯ ÕÂÎÐÈÕ ÍÀ ÃÎÑÒÐÈÉ ÊÎÐÎÍÀÐÍÈÉ ÑÈÍÄÐÎÌ Ç ÏÅÐÑÈÑÒÓÞ×ÎÞ ÃÅÐÏÅѲÐÓÑÍÎÞ ²ÍÔÅÊÖ²ªÞ ßêîâëåâà Ë.Ì., Ïåðåìîò ß.Î., Ïåðåìîò Ñ.Ä., Ñì³ëÿíñüêà Ì.Â., Êàøïóð Í.Â., Âîëÿíñüêèé À.Þ., Àëî³ç Áîìáà, Äàíêîâè÷ Î.Ì. PROMISING USE OF ANTIVIRAL AGENTS IN THE TREATMENT OF PATIENTS WITH ACUTE CORONARY SYNDROME AND PERSISTENT HERPES VIRUS INFECTION Yakovleva L., Peremot J., Peremot S., Smelyanskaya M., Kashpur N., Volyanskiy A., Alois Bomba, Dankovich A. Under
the influence of specific antiviral immunoglobulin treatment reduced
the level of CRP was 2.4-fold, TNF-α by 2.3-fold, and IF leukocytes by
24%.Dynamics of lipoprotein parameters in patients with ACS at high
risk of coronary events, after the application of specific
imunoglobulinoterapii shows a decline in CA and 1.5 times tended to
normalize the levels of LDL-C and HDL-C.Stabilization of coronary heart
disease in a subgroup of patients treated with anti-immunoglobulin,
nearly one and a half times higher than patients with GCS group who
received only conventional basic therapy, accompanied
by clinical deterioration in 13.3% of patients
and resulted in 2 cases of fatal coronary events.
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293-297 |
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| IÇÎÏÐÅÍίÄÍÈÉ ÑÊËÀÄ ÑÈÐÎÂÈÍÈ VISCUM ALBUM Óïèð Ä.Â., Êèñëè÷åíêî Â.Ñ., Ìàðòèíîâ À.Â. IZOPRENOIDS COMPOSITION OF THE VISCUM ALBUM RAW MATERIAL Upyr D.V., Kyslychenco B.S., Martynov A.V. Qualitative
and quantitative composition of terpenoids in the Viscum album L.
raw material, harvested from different trees of the host (linden and
poplar), has been studied by gas chromatography method. The content of
terpenoids in grass mistletoe was 0.28% and 0.14% respectively. It was
determined 133 compounds are compounds were identified. Among the
identified compounds 35 were found in both extrakts, 9 - only in
mistletoe harvested from lime (1.8-cineole,
camphor, β-evdesmol, etc.), 19 substances -
only in mistletoe harvested from poplar (α-isophorone, β-farnesene,
β-ionone, farnesol, α-bisabolol etc).
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298-302 |
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| ÇÀÂÈÑÈÌÎÑÒÜ ÊËÈÍÈ×ÅÑÊÎÉ ÊÀÐÒÈÍÛ ÐÎÒÀÂÈÐÓÑÍÎÉ ÌÎÍÎ- È ÌÈÊÑÒ-ÈÍÔÅÊÖÈÈ Ó ÄÅÒÅÉ ÎÒ ÈÑÕÎÄÍÎÃÎ ÓÐÎÂÍß ÈÍÒÅÐËÅÉÊÈÍΠÊèðñàíîâà Ò.À. DEPENDENCE OF CLINICAL MANIFESTATION OF ROTAVIRAL MONO- AND MIXED INFECTION AT CHILDREN FROM INITIAL LEVEL OF INTERLEUKINS Kirsanova T.A. The
article presents the results of the study of definition the cytokine
status at children with rotaviral and rotaviral-bacterial infections
and communication revealing between indicators of level interleukins
and clinical manifestation of disease. Reliable direct connection
between the level of interleukins and clinical manifestation of disease
has been detected. It appears to be the factor which regulates
inflammatory process, and causes the formation of pathological process
in the gastrointestinal tract and the systemic inflammatory answer.
That in the whole defines the presence and full-blown character of the
clinical displays of the disease.
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303-306 |
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| ÔÎÒÎÄÈÍÀ̲×ÍÈÉ ÂÏËÈ ÍÀ ÏËÀÍÊÒÎÍͲ ÔÎÐÌÈ É Á²ÎÏ˲ÂÊÈ ²ÇÎËßҲ S. PYOGENES, S.AUREUS ÒÀ PROTEUS SPP. Öèãàíåíêî À.ß., ̳øèíà Ì.Ì., Äóáîâèê Î.Ñ., ̳øèí Þ.Ì. PHOTODYNAMIC INFLUENCE ON PLANKTON FORMS AND BIOFILMS OF S. PYOGENES, S. AUREUS AND PROTEUS SPP. ISOLATES Tsyganenko A.J., Mishina Ì.M., Dubovik E.S., Mishin Y.M. The effect
of blue and red light diode radiation was studied on the plankton forms
and biofilms of bacteria, causative agents of purulent inflammatory
processes, depending on chronoinfrastructure. It was revealed that
isolates reacted differently on the light diode radiation: the blue
light mainly inhibited the ability of biolofilm production by plankton
cells and the ability of preformed biofilms to produce plankton cells,
while the red light in most cases did not influence the formation of
primary biofilm and inhibited the release of plankton cells by the
preformed biofim to a less extent.
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307-311 |
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| ÏÐÅÏÀÐÀÒÛ ÍÀ ÎÑÍÎÂÅ ÔÅÍÎËÜÍÎÉ ÃÈÄÐÎÔÈËÜÍÎÉ ÑÓÁÑÒÀÍÖÈÈ ÏÐÎÏÎËÈÑÀ È ÈÕ ÏÐÈÌÅÍÅÍÈÅ Â ÒÅÐÀÏÈÈ ÈÍÔÅÊÖÈÎÍÍÛÕ ÇÀÁÎËÅÂÀÍÈÉ Ðàä÷åíêî Å.À., Øóëüãà Í.Í., Ãóøèëèê Á.È., Àëüõóñåéí Ìóñòàôà Àëè, ×åðíÿåâà Ñ.À. PREPARATIONS ON BASIS OF PHENIC HYDROPHILIC SUBSTANCE OF PROPOLIS AND THEIR APPLICATION ARE IN THERAPY OF INFECTIOUS DISEASES. Radchenko E.A., Shulga N.N., Gushilik B.I., Al'khuseyn Mustafa Ali, Chernyaev S.A. The
problem of search of effective antibacterial preparations is
conditioned high morbidity and wide prevalence of infectious diseases.
In spite of intensive skrining, conducted in the whole world, the
amount of antibacterial preparations at the row of infections is
limited. We are study antibacterial and antivirus activity of
terapevticheskikh preparations on the basis of phenic hydrophilic
substance of propolis and perspective of their use is rotined for
treatment of infectious diseases. Study clinical efficacy "Propoltin"
and «Propomedin». Which are created on the basis of phenic hydrophilic
faction of propolis and the prospect of their application is rotined in
treatment of infectious diseases.
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312-313 |
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| ÃÅÍÎÒÈÏÈÐÎÂÀÍÈÅ
ÑHLAMYDIA TRACHOMATIS, ÂÛßÂËÅÍÍÛÕ Â ÎÁÐÀÇÖÀÕ, ÏÎËÓ×ÅÍÍÛÕ Ó ÁÎËÜÍÛÕ Ñ
ÓÐÎÃÅÍÈÒÀËÜÍÎÉ ÏÀÒÎËÎÃÈÅÉ Â ÑÅÂÅÐÎ-ÂÎÑÒÎ×ÍÎÌ ÐÅÃÈÎÍÅ ÓÊÐÀÈÍÛ Ëèòîâ÷åíêî Î.À. GENOTYPING OF ÑHLAMYDIA TRACHOMATIS OBTAINED FROM PATIENTS WITH UROGENITAL PATHOLOGY IN NORTH-WEST REGION OF UKRAINE Lytovchenko O. The
genotype distribution of Chlamydia trachomatisin patients with
urogenital pathology in North-West region of Ukraine was investigated
with aid of restriction analysis. The most prevalent genotypes were E,
G and F, detected in 24 %, 23,5% è 21,2 % of cases.
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314-315 |
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| ÂÏËÈ ԲÇÈ×ÍÈÕ ÒÀ Ô²ÇÈÊÎ-ղ̲×ÍÈÕ ×ÈÍÍÈʲ ÍÀ ²ÌÓÍÎÁ²ÎËÎò×Ͳ ÂËÀÑÒÈÂÎÑÒ² ÄÈÔÒÅвÉÍÎÃÎ ÒÎÊÑÈÍÓ Êàë³í³÷åíêî Ñ.Â., Áàáè÷ ª.Ì., ʳââà Ô.Â., Ðÿáîâ³ë Î.Â., Ãîðáóíîâ Ë.Â., Ðèæêîâà Ò.À., Ñêëÿð Í.²., Êîâàëåíêî Î.²., Êàòð³÷ Â.Î., Æäàìàðîâà Ë.À., Áîáèðåâà ².Â., Àíòóøåâà Ò.²., Êàë³í³÷åíêî Î.Î. THE INFLUENCE OF PHYSICAL AND PHYSICOCHEMICAL FACTORS ON IMMUNOBIOLOGICAL PROPERTIES OF DIPHTHERIA TOXIN Kalinichenko S.V., Babych, E.M., Kivva F.V., Ryabovol E.V., Gorbunov L.V., Ryzhkova T.A., Sklyar N.I., Kovalenko O.I., Katrych V.A., Zhdamarova L.A., Bobyreva I.V., Kalinichenko E.O. The
influence of physical (ultrasound, temperature) and physicochemical
(formalin, temperature, ultrasound) factors on the
immunobiological properties of diphtheria
toxin and its modifications was
studied. It was established that exposure of these physical
factors did not lead to the destruction and inactivation of the native
diphtheria toxin. Formalin volume fraction reduction by half did not
significantly affect the specific activity and safety of diphtheria
toxin. Ultrasonication of the samples with formalin resulted in
reduction of epidermal reaction up to the total absence of any signs of
hyperemia. It was determined that certain diphtheria toxin derivatives,
obtained by physical and chemical factors, are nonhazardous.
|
316-320 |
|
